钻颅引流辅助尿激酶纤溶治疗高血压脑出血的临床效果  

Clinical effects on microinvasive treatment of hypertensive intracranial hematomas with drainage plus urokinase fibrolysis

作　　者：詹煌金 王鹏[2] 李亦明[1] 

机构地区：[1]五华县人民医院神经外科,梅州514411 [2]广东省人民医院神经外科

出　　处：《临床神经外科杂志》2016年第4期301-303,共3页Journal of Clinical Neurosurgery

摘　　要：目的研究小孔钻颅血肿抽吸引流辅助尿激酶纤溶治疗高血压脑出血的临床效果。方法回顾性分析103例经小孔钻颅血肿抽吸引流辅助尿激酶纤溶治疗的高血压脑出血患者的临床资料,并与内科保守治疗的患者进行比较。观察、比较治疗后患者的血肿清除率/d、住院时间、病死率与预后及生存质量。结果手术治疗组的死亡率明显低于对照组;手术治疗组的血肿清除/吸收时间为(7±2)d、平均住院时间(15±5)d,保守治疗组的血肿清除/吸收时间为(18±5)d、平均住院时间(21±7)d;手术治疗组均明显短于保守治疗组(均P<0.05)。结论钻颅引流辅助尿激酶纤溶治疗高血压脑出血的效果优于内科保守治疗。Objective To explore the clinical effects of drainage plus urokinase in the treatment of hypertensive intracranial hemorrhage .Methods Clinical data of 103 cases with hypertensive intracranial hemorrhage , treated with drainage plus urokinase fibrolysisi were analyzed retrospectively .Patients treated with conservative treatments were used as control group.Results After the treatments, hematoma clearance rate per day , hospital stays, mortality and quality of life between the two groups were compared .Results Mortality in surgical treatment group was lower than that in control group .Hematoma clearance and absorption time in surgical treatment group was （7 ± 2） days, and the average length of hospital stay was （15 ±5） days.While hematoma clearance and absorption time in surgical treatment group was （ 18 ±5 ） days, and the average length of hospital stay was （ 21 ±7 ） days. Conclusions Drainage plus urokinase fibrolysisi is superior to conservative treatments for the treatment of hypertensive intracranial hemorrhage .

关 键 词：高血压脑出血 小孔钻颅 尿激酶纤溶 

分 类 号：R651.1[医药卫生—外科学]