思诺思治疗合并睡眠障碍的主观性耳鸣疗效分析  

Effects of Stilaox on Subjective Tinnitus Patients with Sleep Disorders

作　　者：韩艳艳 布荣霞 李芳 

机构地区：[1]乌鲁木齐市眼耳鼻喉专科医院,乌鲁木齐830002

出　　处：《听力学及言语疾病杂志》2016年第5期457-460,共4页Journal of Audiology and Speech Pathology

摘　　要：目的分析思诺思对合并睡眠障碍的主观性耳鸣患者的疗效。方法采用随机、双盲的对照方法,将68例合并睡眠障碍的主观性耳鸣患者随机分为治疗组和对照组各34例,对照组给予银杏叶提取物(金纳多片)及甲钴胺片(弥可保)口服治疗,治疗组在此基础上加思诺思临睡前口服,并对全部研究对象治疗前及治疗两周后分别进行耳鸣残疾评估量表(tinnitus handicap inventory,THI)及匹兹堡睡眠质量指数(pittsburgh sleep quaIity index,PSQI)评估。结果治疗组治疗后的THI评分(31.94±17.501分)和PSQI评分(4.68±4.132分)均较治疗前(分别为51.88±18.725、13.47±3.38分)明显改善,差异有统计学意义(均为P<0.05);对照组治疗后的THI评分(42.06±18.55分)和PSQI评分(12.24±3.742分)较治疗前(分别为50.29±16.88和13.59±3.43分)显著改善,差异有统计学意义(均为P<0.05)。治疗后治疗组THI和PSQI评分较对照组改善更明显,差异有统计学意义(均为P<0.05)。结论思诺思能改善合并睡眠障碍的主观性耳鸣患者的耳鸣严重程度和睡眠障碍。Objective To study whether stilnox intervention could prove the prognosis for subjective tinnitus patients combined with sleep disorders. Methods By random and double--blind method, 68 tinnitus patients with sleep disorders were randomly divided into the treatment group and control group, with 34 cases in each group. The patients in the control group received ginaton and methycobal oral administration. On the basis of this, the patients in the treatment group received Stilnox oral administration before sleep. All objects of study were evaluated using Tinnitus handicap inventory （THI） and Pittsburgh sleep quality index （PSQI） two weeks before and weeks after treatment. Results The tinnitus disability in the treatment group showed statistical differences before and after treatment （t=8. 810, 〈0.05）. The levels of sleep disorders in the treatment group showed statistical differences after treatment （t= 20. 446, 〈0.05）. The tinnitus disability in the control group showed statistical differences after treatment（t= 6. 900, 〈0.05）. The sleep disorders in the control group showed statistical differences before and af- ter treatment（t=4. 631, 〈0.05）. The tinnitus disability （t=2. 313, 〈0.05） and sleep disorders（t=7. 906, 〈0. 05） after treatment showed statistical differences between the treatment group and control group. Conclusion Stil- nox intervention therapy could improve the prognosis of subjective tinnitus patients with sleep disorders.

关 键 词：思诺思 睡眠障碍 耳鸣 

分 类 号：R764.45[医药卫生—耳鼻咽喉科]