优化药物治疗慢性缺血性心力衰竭及ICD植入状况分析  

Optimal medical therapies for chronic ischemic heart failure and status of ICD implantation

作　　者：王韶屏[1] 廖玮[2] 许振业 秦宇君 李世英[1] 王健[1] 程姝娟[1] 柳景华[1] 

机构地区：[1]首都医科大学附属北京安贞医院心内科28病区,北京市心肺血管疾病研究所,北京100029 [2]四川省医学科学院·四川省人民医院,四川成都610072

出　　处：《实用医院临床杂志》2016年第5期81-83,共3页Practical Journal of Clinical Medicine

基　　金：国家重点基础研究发展计划(973计划)(编号:2015CB554404);国家自然科学基金青年科学基金资助项目(编号:81000131);北京市自然科学基金资助项目(编号:7122058)

摘　　要：目的 评价慢性缺血性心力衰竭优化药物治疗效果及植入式心律转复除颤器（ICD）植入状况。方法 纳入2015年1~10月心内科收治的射血分数（EF）≤0.40的慢性缺血性心力衰竭患者81例,接受优化药物治疗3个月后评估EF和脑钠肽（BNP）变化,并分析ICD植入状况。结果 共76例患者完成治疗和随访,EF值较治疗前显著升高,BNP较治疗前显著降低,差异均有统计学意义（P〈0.05）。有ICD适应证患者植入ICD比例仅29%。结论 优化药物治疗可改善缺血性心力衰竭患者心功能,但ICD植入比例严重不足。Objective To evaluate the effective of optimal medical therapies on ischemic heart failure and status of implantable cardioverter defibrillator （ICD）. Methods This study involved 81 consecutive patients with ejective fraction （EF） ≤ 0. 40 due to ischemic cardiomyopathy in Beijing Anzhen Hospital and Sichuan Provincial People＇s Hospital between January 2015 and October 2015. The EF value and BNP were evaluated after 3 months of the therapies and implantation status of ICD was analyzed. Results Seventy- six patients completed the therapies and follow-up. The EF values were significantly increased while BNP levels were significantly de- creased after the therapies when compared to before treatment （P 〈 0. 05）. Only 29% patients with ICD indications received ICD im- plantation. Conclusion The optimal medical therapies improve cardiac function of patients with ischemic heart failure. The ICD implantation rate was severe insufficient.

关 键 词：心力衰竭 心肌缺血 药物治疗 植入式心律转复除颤器 

分 类 号：R541.4[医药卫生—心血管疾病]