小儿银翘颗粒提取工艺考察  

Study on Extraction Process of Xiaoer Yinqiao Granules

作　　者：刘劲峰[1] 陈画虹[1] 殷爱强[1] 杨小川[1] 鲍涵[2] 

机构地区：[1]中山市博爱医院药学部,广东中山528400 [2]广州中医药大学

出　　处：《中国药师》2016年第9期1760-1762,共3页China Pharmacist

基　　金：中山市科技计划项目(编号:2014A1FC140)

摘　　要：目的:以正交试验法确立小儿银翘颗粒的最佳提取工艺。方法:采用正交试验法,以连翘酯苷A、绿原酸的含量为指标,考察了加水量、提取次数、提取时间三因素对连翘酯苷A、绿原酸的提取量的影响。结果:小儿银翘颗粒的最佳提取工艺为以8倍量、6倍量、6倍量水煎煮三次,提取时间分别为1.5,1,1 h。结论:该提取工艺简单、合理、可行。Objective： To establish the optimal extraction technology of Xiaoer Yinqiao granules by orthognnal test. Methods： The effects of water amount,extraction duration and extraction times were investigated by orthogonal design using the contents of forsythiaside A and chlorogenic acid as the indices. Results： The optimum extraction process was as follows： adding 8-fold amount of water, and extracting 1.5 h for the first time, and then adding 6-fold amount of water, extracting 1 h for the second and third time, respectively. Condusion： The extraction technology is simple, reasonable and reliable.

关 键 词：小儿银翘颗粒 正交试验 连翘酯苷A 绿原酸 提取工艺 

分 类 号：R284.2[医药卫生—中药学]