白花败酱化学成分研究  

Chemical Constituents from Patrinia villosa

作　　者：宋敬丽[1] 袁林[2] 李收[1] 王志亮[1] 

机构地区：[1]枣庄科技职业学院,山东枣庄277599 [2]湖北民族学院风湿性疾病发生与干预湖北省重点实验室,湖北恩施445000

出　　处：《中药材》2016年第5期1038-1040,共3页Journal of Chinese Medicinal Materials

摘　　要：目的:研究白花败酱的化学成分。方法:采用硅胶柱层析、Sephadex LH-20等色谱方法进行分离纯化,依据理化性质及波谱数据进行结构鉴定。结果:从白花败酱乙醇提取物中分离得到6个化合物,分别鉴定为:8,9-didehydro-7-hydroxydolichodial-1-dimethyl acetal(1)、8,9-didehydro-7-hydroxydolichodial(2)、熊果酸(3)、3-O-甲基槲皮素(4)、木犀草素(5)、山柰酚-3-O-阿拉伯糖苷(6)。结论:其中,化合物1为新裂环环烯醚萜,化合物2、4、6为首次从败酱属植物中分离得到。Objective： To investigate the chemical constituents from the ethanol extract of Patrinia villosa. Methods： Various column chromatographic methods including silica gel and Sephadex LH-20 were used for the isolation and purification. Chemical structures were elucidated on the basis of spectroscopic analysis. Results： Six compounds were isolated and identified as 8,9-didehydro-7-hydroxydolichodial-1-dimethyl acetal（ 1）,8,9-didehydro-7-hydroxydolichodial（ 2）,ursolic acid（ 3）,3-O-methylquercetin（ 4）,luteolin（ 5） and kaempferol-3-O-arabinoside（ 6）. Conclusion： Compound 1 is a new secoiridoid,and compounds 2,4,6 are isolated from the Patrinia genus for the first time.

关 键 词：白花败酱 8 9-didehydro-7-hydroxydolichodial-1-dimethyl ACETAL 新裂环环烯醚萜 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]