超高效液相色谱-质谱法测定儿童产品中苏丹红Ⅰ、四溴双酚A和两种磷酸酯  

Determination of Phosphates,Tetrabromobisphenol A and Sudan Ⅰin Children Products by Ultra Performance Liquid Chromatography-Mass Spectrometry

作　　者：赖莺[1] 林睿[1] 林伟靖[1] 葛秀秀[1] 董清木[1] 李彬[2] 丁华军[1] 林海霞[1] 涂星朋[1] 陈小玲[1] 叶淑爱[1] 

机构地区：[1]厦门出入境检验检疫局技术中心,厦门361026 [2]深圳职业技术学院,深圳518055

出　　处：《分析化学》2016年第8期1236-1242,共7页Chinese Journal of Analytical Chemistry

基　　金：国家质检总局科研项目(Nos.2014IK160,2015IK186)资助

摘　　要：建立了儿童产品中4种高关注物质（苏丹红玉、四溴双酚A、磷酸三（1,3-二氯-2-丙基）酯、磷酸三（2-氯丙基）酯）同时检测的超高效液相色谱-质谱检测方法。样品经乙腈超声萃取后,选择C18柱在3 min内分离4种待测物质。结果表明,本方法所测各物质的定量限为5-500μg/kg。在2-3个数量级浓度范围内,线性相关系数均在0.9995以上。在3个添加水平下,平均回收率为83.7%-97.8%,相对标准偏差（n=6）小于5%。本方法操作简单快捷,灵敏度、回收率高,选择性好,能满足实际工作的要求。A reliable UPLC-MS method was developed for the simultaneous determination of 4 chemicals （Sudan Ⅰ, tetrabromobisphenol A, tris （ 1, 3-dichloroisopropyl ） phosphate and tris （ chlorisopropyl ） Phosphate） in children products. The samples were ultrasonic extracted with acetonitrile, and then the four chemicals were separated on a C18 column in 3 min. Results showed that the limit of quantification of the method was between 5 and 500μg/kg. The calibration curves were linear within 2-3 orders of magnitude with typical correlation coefficient above 0 . 9995 . The recoveries ranged from 83 . 7% to 97 . 8% with three addition levels. The sensitivity, recovery and selectivity of the method could fully meet the requirements of practical work.

关 键 词：儿童产品 高关注物质 磷酸酯 四溴双酚A 苏丹红I 超高效液相色谱-质谱法 

分 类 号：O657.63[理学—分析化学] TS958.07[理学—化学]