国产单腔球囊、COOK双球囊、小剂量催产素在足月引产的临床效果比较  

作　　者：冯惠庆[1] 金海英[1] 庞剑霞[1] 黄锡欢[1] 高锦雯[1] 

机构地区：[1]南方医科大学附属中山博爱医院,广东中山528400

出　　处：《世界中医药》2016年第B03期1443-1444,共2页World Chinese Medicine

摘　　要：目的为足月妊娠计划分娩引产提供更合适的方法。方法：采用病例对照研究的方法，选择180例具备引产指征的宫颈评分≤6分足月妊娠产妇，把研究对象分成3组，应用进口Cook宫颈扩张球囊为A组，应用小剂量催产素为B组，应用国产球囊为c组，每组各60例。比较各组应用后孕妇的Bishop评分、引产至分娩的时间、计划分娩成功率、分娩结局、母亲并发症及新生儿情况。结果：A组促宫颈成熟有效57例（95．0％），水囊脱落3例；B组有效22例（36．0％）；C组有效59例（98．％），水囊脱落1例；A、C组与B组相比，差异有统计学意义（P〈0．05）。A、C组引产至分娩时间所需时间比B组所需时间短，差异有统计学意义（P〈0．05）。A、C组计划分娩成功率分别53例（84．096）、54例（90％），差异无统计学意义（P〉0．05），B组组计划分娩成功率较低，9例（15．0％）。A、C组经阴道分娩分别44例（74．0％）；48例（80．O％），差异无统计学意义（P〉0．05），B组13例（21．096）。3组产褥感染率及新生儿出生时状况无明显差异。结论：进口Cook宫颈扩张球囊、国产球囊均有明显的促宫颈成熟作用，均优于小剂量催产素，且两者的治疗效果差异无统计学意义，国产球囊费用相对低，经济实用性更佳。Objective Purpose To provide a more appropriate method for induction of labor at term pregnancy. Methods： A case-control study,including 180 cases of maternal pregnancy which all had the indications for labor induction with the cervical maturity score more than 6 points.The subjects in this study were divided into three groups, using the COOK double balloon, small dose of oxytocin and domestic single lumenballoon as group A,B,C relatively, with 60 cases in each. Compared with the Bishop score, the time between labor and delivery, the rate ofdelivery, the delivery outcome, and the maternal and neonatal complications in each group separately. Results： With the result promotingcervical ripening, 57 cases （95%） in group A, 22 cases （36%）in group B, 59 cases （98%） in group C, and with 3 cases and lease the balloonabscission relatively. Compared Group A, Group C to Group B, the difference was statistically significant （P〈0．05）. The time between labor anddelivery in Group A and C was less than Group B, and the difference was statistically significant （P〈0.05）. The rate of delivery in Group A andC is 84.0%（53 cases） and 90.0%（54 cases）, ti,e difference was not statistically significant （P〉0.05）, but the rate of Group is only 15.0%. GroupA and C by vaginal delivery were 44 cases（74.0%） and 48 cases（80.0%）, the difference was not statistically significant （P〉0.05）, but in Group Bwere only 13 cases （21.0%）. Puerperal infection and neonatal birth condition had no significant difference in the three groups. Conclusion： Topromote cervical mature, the imported COOK balloon and the domestic balloon were effective, which were better than the small dose ofoxytoein. What＇s more, there is no significant difference between the two treatment. It is more economic utility for domestic balloon to use.

关 键 词：国产单腔球囊 COOK双球囊 小剂量催产素 足月引产 

分 类 号：R719[医药卫生—妇产科学]