妊娠期病原体感染胎儿产前超声诊断的研究  

Value of prenatal ultrasound in diagnosis of abnormal growth of fetuses of pregnant women with pathogens infections

作　　者：孙建东[1] 朱秀堂[1] 张海静[1] 蒋延伟[1] 张学娜[1] 

机构地区：[1]滨州市人民医院特检科,山东滨州256600

出　　处：《中华医院感染学杂志》2016年第17期4050-4052,共3页Chinese Journal of Nosocomiology

基　　金：山东省自然科学基金资助项目(ZR2009CL018)

摘　　要：目的探讨产前超声对妊娠期病原体感染胎儿的诊断评估,为妊娠期病原体感染异常胎儿提供临床诊断依据。方法选取2014年6月-2015年6月接受产前常规TORCH筛查的孕妇920例作为研究对象,采用ELISA法对孕妇进行TORCH-IgM检测,对TORCH-IgM阳性孕妇进行超声检查,并将检测结果与妊娠结局统计结果进行比对分析。结果 920例孕妇中发生病原体感染286例,感染率为31.09%;对其中180例TORCHIgM阳性感染者进行超声检查,发现41例感染者超声检查提示子宫内胎儿发育异常,异常率为22.78%;妊娠结局统计发现,正常分娩者中的TORCH感染率为11.94%;妊娠结局不佳者中的TORCH感染率为54.43%,与正常分娩者中的TORCH感染率相比,差异有统计学意义(P<0.05)。结论产前超声能显示出病原体感染孕妇的胎儿异常,参考孕妇血清检测结果,能为临床孕妇的胎儿异常诊断提供依据。OBJECTIVE To explore the value of prenatal ultrasound in diagnosis of abnormal growth of fetuses of pregnant women with pathogen infections so as to provide guidance for clinical diagnosis of abnormal growth during the pregnancy.METHODS A total of 920 pregnant women who received the routine prenatal TORCH screening examination in the hospital from Jun 2014 to Jun 2015 were recruited as the study objects,then the TORCH-IgM was detected for the pregnant women by using ELISA,the ultrasonography was performed for the pregnant women who were positive for TORCH-IgM,and the test results were compared with the pregnancy outcomes.RESULTS The infections occurred in 286 of 920pregnant women,with the infection rate 31.09%;the ultrasonography was conducted for 180 pregnant women who were tested positive for TORCH-IgM,and the ultrasonography result showed that 41 pregnant women with infections had intrauterine fetal abnormalities,with the abnormal rate22.78%.The statistical analysis of the pregnancy outcomes revealed that the incidence of TORCH infection was11.94%in the normal delivery objects,the incidence of TORCH infection was 54.43%in the objects with poor pregnancy outcomes,and there was significant difference in the incidence of TORCH infection between the normal delivery objects and the objects with poor pregnancy outcomes（P〈0.05）.CONCLUSIONThe prenatal ultrasonography can show the fetal abnormalities of the pregnant women with pathogens infections,and the serological test results can provide guidance for clinical diagnosis of the fetal abnormalities.

关 键 词：孕妇 超声 病原体感染 血清检测 TORCH-IGM 

分 类 号：R445.1[医药卫生—影像医学与核医学]