中药灌肠对肝硬变患者外周血流动力学及ET、ED、NO的影响  

The Influence of TCM Enema on Peripheral Blood Flow Mechanics and ET and ED and NO of Patients with Cirrhosis of Liver

作　　者：司华 贾琦 丁屈顺 

机构地区：[1]镇安县医院,陕西镇安711500 [2]唐都医院,陕西西安710038

出　　处：《河南中医》2016年第8期1370-1372,共3页Henan Traditional Chinese Medicine

摘　　要：目的:观察中药灌肠对肝硬变患者外周血流动力学及ET、ED、NO的影响。方法:选取2011年2月—2015年3月收治的肝硬变患者80例,随机均分为对照组和观察组各40例,对照组行常规治疗,观察组在对照组治疗的基础上加用逍遥散灌肠治疗。结果:观察组显效率与有效率均明显高于对照组(P<0.05);观察组肝门静脉与脾静脉内径以及血流量改善程度明显优于对照组(P<0.05);外周血ET、ED、NO水平均明显低于对照组(P<0.05)。结论:中药保留灌肠治疗能够有效改善肝硬变患者的临床症状,减少腹水,改善肝脾静脉血流动力学指标,降低ED、ET、NO含量。Objective： To observe the clinical curative effect of TCM enema on peripheral blood flow mechanics and ET and ED and NO of patients with cirrhosis of liver. Methods： Eighty patients who were treated in our hospital between Feb. of 2011 and March of 2015 were chosen as the research objects,and randomly divided into the control group and the observation group,with40 cases in each group. The ones in the control group were given routine Western medicine treatment,while the ones in the observation group were added Supplemented Xiaoyao Powder based on the treatment of the control group. Results： The remarkably effective rate and the effective rate of the observation group were much higher than those of the control group（ P〈0. 05）. The improved degrees of hepatic portal vein and splenic vein diameter and blood flow of the observation group were significantly better than those of control group（ P〈0. 05）; Its peripheral blood ET,ED,NO levels were significantly lower than those of the control group（ P〈0. 05）. Conclusion： TCM enema treatment can greatly improve the clinical symptoms,reduce ascites,improve hepatic portal vein and splenic vein blood flow mechanics,reduce contents of ET,ED,NO.

关 键 词：肝硬变 加味逍遥散 灌肠治疗 血流动力学 ET ED NO 

分 类 号：R259.752[医药卫生—中西医结合]