磁共振对BMI正常人群髓核体积的测量与临床应用研究  

Measurement of Nucleus Pulposus Volume by Magnetic Resonance Imaging in Population with Normal BMI

作　　者：文兵[1] 杜瑛[1] 胡良波[1] 张翱[1] 梁学恒 余洁[1] 

机构地区：[1]重庆医科大学附属永川医院放射科

出　　处：《中国医学计算机成像杂志》2016年第4期346-350,共5页Chinese Computed Medical Imaging

基　　金：重庆市卫生局面上资助项目No.2013-2-075~~

摘　　要：目的：定量研究身高体重指数（BMI）正常的人群椎间盘髓核体积,并探讨其临床应用价值。方法：分析310例BMI正常人群的腰椎磁共振图像,运用磁共振图像处理系统测量FSE-T2WI上腰椎各节段椎间盘髓核的体积。根据年龄不同分为青年组（22-44岁）,中年组（45-59岁）,老年组（60岁以上）三个组,对不同年龄组男女性的L1/2-L5/S1节段椎间盘髓核进行体积测量和统计学分析。结果：青年组L1/2-L5/S1椎间盘髓核体积男性分别为：2523.50±627.55mm3,3178.89±803.77mm3,3686.88±897.43mm3,3913.35±749.00mm3,3086.26±928.92mm3,女性分别为1922.42±659.36mm3,2248.56±847.48mm3,3066.38±968.56mm3,3124.99±917.92mm3,2818.81±1022.87mm3。中年组L1/2-L5/S1椎间盘髓核体积男性分别为：2502.27±821.06mm3,3056.98±965.97mm3,3629.82±1219.14mm3,3858.20±1035.57mm3,3037.07±834.51mm3,女性分别为1991.65±638.32mm3,2383.49±723.42mm3,2989.30±851.11mm3,3165.12±885.84mm3,2787.01±762.72mm3;老年组L1/2-L5/S1椎间盘髓核体积男性分别为：2455.86±776.34mm3,3019.00±676.15mm3,3515.96±809.14mm3,3802.23±721.39mm3,2984.83±706.73mm3,女性分别为：2030.78±604.28mm3,2246.92±622.53mm3,2812.35±833.55mm3,3020.11±899.33mm3,2750.87±852.667mm3。同年龄组L1/2-L5/S1节段男女之间正常髓核体积差异均有显著性统计学意义（P〈0.01）,同节段不同年龄组之间正常髓核体积差异均无统计学意义（P〉0.05）,统计节段中相邻两髓核体积存在相关关系,各节段髓核体积与BMI指数相关性不大,而分别与身高和体重具有一定的相关性。结论：本研究测量了正常成人腰椎间盘髓核体积正常范围,为椎间盘髓核假体体积以及其他科学实验提供方法和参考标准。Purpose： To quantitative study the volume of nucleus pulposus of lumbar intervertebral disc in population with normal body mass index（BMI）, and to explore its clinical application value. Methods： Three hundred and ten patients who were investigated by lumbar MRI were analyzed retrospectively. The measurement was carried out based on sagittal FSE-T2 WI images, and then the volumes of nucleus pulposus were calculated. The cases were divided into the young group（22 to 45 years old）, the middle age group（46-60 years old）, and the elder group（60 years） according to their age, and the volume of L1/2-L5/S1 nucleus pulposus of the males and females in each group were measured and statistically analyzed respectively. Results： The young group： the volume of L1/2-L5/S1 nucleus pulposus of males was 2523.50±627.55mm3,3178.89±803.77mm3,3686.88±897.43mm3,3913.35±749.00mm3,3086.26±928.92mm3, respectively, and the volume of L1/2-L5/S1 nucleus pulposus of females was 1922.42±659.36mm3,2248.56±847.48mm3,3066.38±968.56mm3,3124.99±917.92mm3,2818.81±1022.87mm3, respectively; The middle age group： the volume of L1/2-L5/S1 nucleus pulposus of males was 2502.27±821.06mm3,3056.98±965.97mm3,3629.82±1219.14mm3,3858.20±1035.57mm3,3037.07±834.51mm3, respectively, and the volume of L1/2-L5/S1 nucleus pulposus of females was 1991.65±638.32mm3,2383.49±723.42mm3,2989.30±851.11mm3,3165.12±885.84mm3,2787.01±762.72mm3, respectively; The elder group： the volume of L1/2-L5/S1 nucleus pulposus of males was 2455.86±776.34mm3,3019.00±676.15mm3,3515.96±809.14mm3,3802.23±721.39mm3,2984.83±706.73mm3, respectively, and the volume of L1/2-L5/S1 nucleus pulposus of females was 2030.78±604.28mm3,2246.92±622.53mm3,2812.35±833.55mm3,3020.11±899.33mm3,2750.87±852.667mm3, respectively. There was statistical significant difference in the volumes of L1/2-L5/S1 nucleus pulposus between the males and females in the same group（P〈0.01）. No statistical significant difference was found in the volumes of the s

关 键 词：椎间盘 髓核 体积 磁共振 

分 类 号：R445.2[医药卫生—影像医学与核医学]