腹腔镜与开腹手术对早期卵巢癌临床疗效评价的随机对照分析  

Randomized controlled analysis on the clinical efficacy of laparoscope surgery and laparotomy in early ovarian cancer

作　　者：王雪梅[1] 马欢[1] 刘婉[1] 高雄杰[1] 李春季[1] 

机构地区：[1]陕西省榆林市第一医院妇产科,陕西榆林719000

出　　处：《中国妇幼健康研究》2016年第8期991-993,共3页Chinese Journal of Woman and Child Health Research

摘　　要：目的探讨腹腔镜与开腹手术对早期卵巢癌临床疗效的比较。方法选取2014年6月至2015年6月榆林市第一医院妇科接诊的44例早期卵巢癌患者,根据随机数字表法分为实验组和对照组,实验组给予腹腔镜手术治疗,对照组给予开腹手术治疗,评价两组的临床疗效差异。结果腹腔镜组和开腹组的手术时间无明显差异(279.23±74.24:268.66±76.13min,P>0.05),但是腹腔镜组的术中出血量(159.44±92.66:381.25±73.16 m L,P=0.002)、术中输血率(0.00%:13.64%,P=0.005)和子宫切除率明显低于开腹组(50.00%:63.64%,P=0.024),差异有统计学意义。腹腔镜组的术后胃肠道恢复时间(1.64±0.76:2.69±0.92天,P=0.002)和住院时间均早于开腹组(10.35±5.11:13.21±6.62天,P=0.001)[子宫切除比例(50.00%:63.64%,P=0.024)也低于开腹组,差异有统计学意义]。两组患者术后化疗率(90.91%:86.36%,P=1.365)和复发率无明显差异(4.55%:9.09%,P=0.784)。术后评价性生活质量和植物神经功能失调症状,2组患者无明显差异(P>0.05)。结论腹腔镜手术具有损伤小、子宫切除率低、术后恢复快、并发症少等优势,在患者术后生活质量的保留上与开腹手术相同,对于早期卵巢癌患者可作为首选治疗。Objective To investigate and compare the clinical efficacy of laparoscope surgery and laparotomy in early ovarian cancer.Methods Totally 44 cases of early ovarian cancer were selected as subjects,who were diagnosed from June 2014 to June 2015 in the First Hospital of Yulin in Shaanxi Province. They were randomly divided into experiment group and control group. The experiment group was given laparoscope surgery,while the control group was treated with laparotomy. The clinical efficacy was compared. Results There was no significant difference in the time of operation（ 279. 23 ± 74. 24 min,268. 66 ± 76. 13 min,P 0. 05） between two groups,while the intraoperative blood loss,intraoperative blood transfusion rate,uterus resection rate in the experiment group were lower than those in the control group（ 159. 44 ± 92. 66 m L,381. 25 ± 73. 16 ml,P = 0. 002）,（ 0. 00%,13. 64%,P = 0. 005）,（ 50. 00%,63. 64%,P = 0.024）,and the differences were statistically significant. Time of resumption of gastrointestinal function after operationand and hospital stays in the experiment group were less than those in the control group（ 1. 64 ± 0. 76,2. 69 ± 0. 92 d,P = 0. 002）,（ 10. 35 ± 5. 11 d,13. 21 ± 6.62 d,P = 0. 001）,and the differences were statistically significant. There was no obvious difference in the postoperative chemotherapy rate and recurrence rate between two groups（ 90. 91%,86. 36%,P = 1. 365; 4. 55%,9. 09%,P = 0. 784）. The quality of sexual life and vegetative nerve functional disturbance scores were not significantly different（ P 〉0. 05）. Conclusion Thanks to many clinical advantages such as non-invasive,low uterus resection rate,fast post operation recovery and fewer complications,laparoscope surgery has same clinical effects as the laparotomy. As such,it can be used as preferred treatment for the patients with early ovarian cancer.

关 键 词：腹腔镜 开腹 早期卵巢癌 随机对照研究 

分 类 号：R713.6[医药卫生—妇产科学]