1990与2013年中国40岁以上人群归因于低骨密度的疾病负担分析  

The burden of disease attributed to low bone mineral density among population aged ≥40 years old in China, 1990 and 2013

作　　者：赵振平[1] 艾红辉[2] 李镒冲[1] 王丽敏[1] 殷鹏[1] 张梅[1] 邓茜[1] 黄正京[1] 刘江美[1] 刘韫宁[1] 高钰杰[1] 周脉耕[1] 

机构地区：[1]中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京100050 [2]南昌大学第一附属医院耳鼻咽喉头颈外科

出　　处：《中华预防医学杂志》2016年第9期782-787,共6页Chinese Journal of Preventive Medicine

基　　金：国家自然科学基金（71420107023）

摘　　要：目的 分析1990与2013年中国40岁以上人群低骨密度导致的疾病负担。方法 利用2013年全球疾病负担研究数据，分析1990与2013年中国（不包括中国台湾）40岁以上人群低骨密度导致的死亡和伤残调整寿命年（DALY），比较1990与2013年归因于低骨密度的DALY的伤害构成和不同省份DALY变化情况；采用2000—2025年世界人口的平均年龄结构作为标准人口进行率的标化。结果 2013年，中国40岁以上人群归因于低骨密度死亡的男性3.81万例，女性3.07万例。中国40岁以上男性因低骨密度造成的DALY（152.5万人年）高于女性（87.3万人年）。1990年低骨密度导致的交通工具伤害和意外伤害的DALY分别为79.4和56.7万人年，2013年分别为142.1和95.1万人年，分别上升79.1％和67.6%。1990年低骨密度导致的交通工具伤害和意外伤害的标化DALY率分别为68.1/10万和48.7/10万，2013年分别为102.0/10万和68.2/10万，分别上升了49.8％和40.2%。2013年中国低骨密度导致的标化DALY率较高的3个省份分别是浙江（2.6/10万）、江苏（2.4/10万）和福建（2.2/10万）；同1990年相比，中国27个省份低骨密度导致的标化DALY率下降，宁夏、青海、河北、广西、河南和新疆6个省份标化DALY率升高。结论 中国40岁以上人群中，男性低骨密度导致的疾病负担高于女性。同1990年相比，2013年中国大多数省份的40岁以上人群的DALY率有所下降，但是交通工具伤害和意外伤害造成的归因于低骨密度疾病负担上升。Objective To identify cause-specific death and attributed burden of low bone mineral density in China among population aged ≥40 years old , 1990 and 2013.Methods By using data from Global Burden of Disease（GBD）2013, this study analyzed death caused by low mineral density, and disability-adjusted life years（DALY）among population aged 40 and above in China（not including Taiwan, China）. This study also analyzed DALY by composition of injury which due to low bone mineral density. It also analyzed changes in DALY by provinces in China, 1990 and 2013. An average world population age-structure for the period 2000- 2025 was adopted to calculate the age standardized rates.Results In 2013, there were 38.1 thousands male and 30.7 thousands female who aged 40 and above dead due to low bone mineral density in China. The burden of injury caused by low bone mineral density was more sever in male than female, which accounted for 1.525 million DALY in male and 0.873 million DALY in female. In 1990, low bone mineral density attributed transportation and accidental injury caused 0.794 million and 0.567 million DALY losses, respectively. In 2013, low bone mineral density attributed transportation and accidental injury caused 1.421 million and 0.951 million DALY losses, respectively. Compared to 1990, DALY losses caused by transportation and accidental injury, increased by 79.1% and 67.6%, respectively. In 1990, DALY rate losses due to low bone mineral density attributed transportation and accidental injury were 68.1 per 100 000 and 48.7 per 100 000, respectively. In 2013, DALY rate losses due to low bone mineral density attributed transportation and accidental injury were 102.0 per 100 000 and 68.2 per 100 000, respectively. Compared to 1990, DALY rates which caused by transportation and accidental injury, increased by 49.8% and 40.2%, respectively. According to the ranking of standardized DALY rate in 2013 by provinces, the top 3 provinces, which standardized DALYs attributed to low bone mineral density lost the mo

关 键 词：中国 骨密度 骨质疏松 疾病负担 

分 类 号：R580[医药卫生—内分泌]