血液核酸检测降低经血传播疾病风险的研究  

Reducing the risk of blood-transmitted diseases by nucleic acid test

作　　者：方奎明 孙昂 吴晓晋 祝青 黄志翔 鲁红霞 易玲 符凯 李轶 

机构地区：[1]岳阳市中心血站,湖南岳阳414000

出　　处：《实用预防医学》2016年第10期1188-1190,共3页Practical Preventive Medicine

基　　金：岳阳市自然科学基金(2014-3-22)

摘　　要：目的探讨血液核酸检测在降低经血传播疾病风险的意义。方法对岳阳血站2015年1-12月采集的40 833份血液,均采用2次血清学检测和1次核酸检测,HIV有反应性标本同时送市疾控中心确诊。结果 40 833份血液标本,经2次血清学检测,39 571份标本无反应性,408份标本HBs Ag、抗-HCV、抗-HIV有反应性;经1次核酸检测,39 571份标本中18份有反应性,408份标本中214份有反应性。结论血液核酸检测能降低经血传播疾病的风险,提高血液安全性。Objective To explore the significance of nucleic acid test in reducing the risk of blood-transmitted diseases. Methods A total of 40,833 blood samples collected from the Central Blood Station of Yueyang City from January to December 2015 were detected by two times enzyme linked immunoassay tests and one-time nucleic acid test. The samples with HIV positive reaction were sent to Yueyang Municipal Center for Disease Control and Prevention for confirmatory test. Results Among the 40,833 blood samples subject to two times of enzyme linked immunosorbent assay, there were 39,571 samples with negative response and 408 with positive hepatitis B surface antigen （ HBsAg） , anti-HCV and anti-HIV. Among the 39,571 samples subject to one-time nucleic acid test, there were 18 samples with positive HBV-DNA. Among the 408 samples with one-time nucleic acid test, there were 214 samples with positive HBsAg, anti-HCV and anti-HIV resuhs. Conclusions Nucleic acid test can reduce the risk of blood-transmitted diseases and improve the safety of blood.

关 键 词：核酸检测 ELISA 经血液传播疾病 血液安全 检测策略 

分 类 号：R446.1[医药卫生—诊断学]