2014年新疆克拉玛依市健康人群麻疹、风疹抗体水平监测分析  

Monitoring and analyzing the levels of measles and rubella antibodies among healthy people in Karamay in 2014

作　　者：李君梅[1] 李霞[1] 黄玉莲[1] 

机构地区：[1]新疆维吾尔自治区克拉玛依市疾病预防控制中心,新疆克拉玛依834000

出　　处：《现代预防医学》2016年第18期3409-3412,共4页Modern Preventive Medicine

基　　金：新疆克拉玛依市科技项目(编号sk2014-54)

摘　　要：目的了解克拉玛依市人群麻疹、风疹抗体水平,有针对性地开展麻疹、风疹免疫预防工作,有效控制麻疹、风疹的发生和流行,实现消除麻疹的目标。方法按照分层随机抽样方法,采集0～60岁健康人群1 056人份血样,采用ELISA方法,定量检测麻疹抗体、风疹抗体。结果人群麻疹抗体阳性率97.54%、风疹抗体阳性率87.22%,抗体几何平均浓度（Geometric Mean Concentration,GMC）麻疹、风疹分别为：1 220.10 m IU/ml、68.23 IU/ml,不同人群麻疹、风疹抗体阳性率差异均有统计学意义（麻疹χ^2=20.170,风疹χ^2=17.090,P均〈0.05）;不同地区麻疹抗体阳性率在95%以上、保护率在65%～75%之间,风疹抗体阳性率在75%～94%之间,不同地区风疹抗体阳性率差异有统计学意义（χ^2=31.106;P〈0.001）;不同免疫史风疹抗体阳性水平差异有统计学意义（χ^2=30.254,P〈0.001）。结论克拉玛依市麻疹人群抗体阳性率总体保持在较高水平,风疹抗体阳性率水平略低,乌尔禾区和部分年龄组风疹阳性率较低。应重点加强地区及重点人群疫苗预防接种管理,必要时开展人群查漏补种免疫。Objective This was to learn the measles and rubella antibody level of people in Karamay, so as to improve the immunization of measles and rubella, effectively control and eradicate measles and rubella. Methods A stratified random sampling method was used to collect 1056 blood samples from people aged 0-60. ELISA method was used for the quantitative determination the antibody level of measles and rubella. Results The antibody positive rate was 97.54% and 87.22% for measles and rubella, respectively. GMC of measles and rubella antibody was 1220.10mIU/ml and 68.23IU/ml, respectively. Both positive rates were statistically significant （X2（measles）=20.170,E2 （rubella）=17.090,P〈0.05）. The positive rates of measles antibody in different region were all above 95%, and the protection rates varied from 65% to 75%. The positive rates of rubella antibody varied from 75% to 94%. The positive rates of rubella antibody in different regions were statistically significant （X2=31.106;P〈0.05）. The positive rate of rubella antibody between different immune stage were statistically significant （E2=30.254,P〈0.01）. Conclusion The positive rate of measles antibody in Karamay kept at a high level and the positive rate of rubella antibody was lower, especially for people in Urho region and of some specific age group. Vaccine immunization management in regions and key groups should be strengthened. The examination of missing doses and re-vaccination should be conducted if necessary.

关 键 词：麻疹 风疹 抗体 

分 类 号：R183.3[医药卫生—流行病学]