2180例胎儿肿瘤的产前超声检查与随访状况分析  

Analysis on prenatal ultrasonographic findings and follow-up of 2180 fetuses with tumors

作　　者：刘云[1] 栗河舟[1] 刘月华[1] 雷冬梅[1] 王芳[1] 

机构地区：[1]郑州大学第三附属医院,河南郑州450052

出　　处：《中国妇幼保健》2016年第18期3857-3859,共3页Maternal and Child Health Care of China

基　　金：河南省科技攻关项目(142102310499);郑州市科学技术局科技发展计划(20140909)

摘　　要：目的 了解胎儿肿瘤的产前超声检出情况,分析失访率及失访原因,以便加强对胎儿肿瘤的产前诊断工作。方法回顾性分析2 180例胎儿肿瘤的临床资料,将孕妇按年龄分为〈25岁、25~35岁、〉35岁3个年龄组;将受检胎儿按孕周分为〈18周、18~24周、24~30周、30~36周、36~41周5个组,比较不同年龄组及不同孕龄组胎儿肿瘤的检出率。根据随访情况把研究对象分为失访组和随访组,分析失访率及失访原因。结果 胎儿肿瘤的总检出率为1.32%（2 180/164 783）,从2011-2015年检出率分别为1.10%、1.23%、1.34%、1.43%、1.47%。胎儿肿瘤检出率在各年龄组间的差异无统计学意义（P〉0.05）,在各孕龄组间的差异有统计学意义（P〈0.05）,多发生在孕中晚期。胎儿肿瘤总失访率32.98%（719/2 180）,从2011-2015年失访率依次为41.82%、37.70%、32.13%、29.45%、28.22%。76.63%的失访原因是患者拒绝尸检。结论 2011-2015年胎儿肿瘤的年检出率呈增长趋势。胎儿肿瘤大多发生于中晚孕期,和孕妇年龄无关,建议加强晚孕期产前检查。Objective To understand the prenatal ultrasonographic results of fetal tumors, analyze the rate and cause of lost to follow- up, strengthen prenatal diagnosis of fetal tumors. Methods The clinical data of 2 180 cases of fetal tumors were retrospectively analyzed. The pregnant women were divided into three groups according to age： ≤25-year-old group, 25-35-year-old group, ≥35-year-old group. The fetuses were divided into five groups according to gestational age： ≤ 18-week group, 18-24-week group, 24-30-wee group, 30-36-week group, 36-41-week group. The detection rates of fetal tumors were compared among different age groups and gestational age groups. According to the follow-up results, the cases were divided into lost group and follow-up group. The rate and reasons of lost to follow-up were analyzed. Results The total detection rate of fetal tumors was 1.32% （2 180/164 783） . .From 2011 to 2015, the detec- tion rate of fetal tumors were 1.10% , 1.23%, 1.34%, 1.43% , and 1.47%, respectively. There was no statistically significant difference in detection rate of fetal tumors among different age groups （ P〉0. 05 ） . There was statistically significant difference in detection rate ＇of fetal tumors among different gestational age groups （ P〈0. 05 ）, fetal tumors mainly occurred during the second and the third trimesters of pregnan- cy. The total lost rate of follow up was 32.98% （719/2 180） . From 2011 to 2015, the lost rates of follow up were 41.82%, 37.70%, 32. 13%, 29.45%, and 28. 22%, respectively. The reason of 76. 63% of lost to follow- up cases was rejection of autopsy. Conclusion The detection rate of fetal tumors showed a rising trend from 2011 to 2015, Most of fetal tumors oceured during the second and the third trimesters of pregnancy, which was not correlated with maternal age. It is advised to strengthen prenatal care during the third trimes- ter of pregnancy.

关 键 词：超声检查 胎儿肿瘤 构成比 检出率 

分 类 号：R714.5[医药卫生—妇产科学]