幽门螺杆菌感染与多项指标的相关性分析  

The relationship of helicobacter pylori infection and FPG,lipid,glucose,uric acid,PLT,PDW and MPV in serum among health population

作　　者：李光友[1] 苏贵灵[2] 

机构地区：[1]安徽省芜湖市第二人民医院检验科,241000 [2]安徽省芜湖市第一人民医院,241000

出　　处：《国际检验医学杂志》2016年第18期2548-2549,2552,共3页International Journal of Laboratory Medicine

摘　　要：目的了解体检人群幽门螺杆菌（Hp）感染状况和分布特点,以及Hp感染与空腹血糖、血脂、尿酸及血小板水平的关系。方法对2013年6~12月来芜湖市第二人民医院进行健康体检的2 147例资料进行回顾性分析,探讨Hp感染与空腹血糖、血脂、尿酸及血小板的相关性。结果 Hp总感染率38.80%（833/2 147）,其中男性Hp感染率41.10%（538/1 309）,女性Hp感染率35.20%（295/838）,男性Hp感染率高于女性（P〈0.05）;40~岁年龄段的人群感染率明显高于其他年龄段（P〈0.05）。Hp阳性组TC、LDL-C的表达水平明显高于阴性组（P〈0.05）,而HDL-C的表达水平明显低于阴性组（P〈0.05）。Hp感染伴TC升高者FPG和UA水平显著高于Hp感染组和阴性组（P〈0.05）。结论体检人群Hp感染率在不同年龄段和性别间存在差异;Hp感染可影响血清脂类、糖类、尿酸的代谢。Objective To investigate the infection status of helicobacter pylori（Hp）among health examination population,and its relationship to lipids,glucose,uric acid,PLT,PDW and MPV.Methods Hp antibody in serum was tested by immune colloidal gold assay among of health population.And serum lipids,glucose,uric acid,PLT,PDW and MPV were measured in some subjects.A retrospective analysis was done to the data of 2 147 cases in health examination population.Results The infection rates of Hp was 38.80%（833/2 147）in 2 147 cases.Among them,the infection rate in male was 41.10%（538/1 309）,and which in female was35.20%（295/838）,it was statistical difference in the infection rate in between male and female（P〈0.05）.The infection rate in age group（40to 49）was higher than which in other age group and It was statistically significant（P〈0.05）,and there were significant difference in between male age group and in female age group（P〈0.05）.Comparing the control group,the serum levels of TC,LDL-C were significantly higher（P〈0.05）,while the serum level of HDL-C was obviously lower（P〈0.05）.In patients with Hp infection and TC5.17mmol/L,the level of glucose and uric acid were significantly higher（P〈0.05）.Conclusion The distribution of the Hp infection was difference in gender and age;The infection of HP can effect the metabolism of serum lipids,glucose and uric acid.

关 键 词：幽门螺杆菌 空腹血糖 血脂 尿酸 血小板 

分 类 号：R446.1[医药卫生—诊断学]