丹红注射液对老年不稳定型心绞痛的疗效及炎性因子水平的影响  

Curative Effect of Danhong Injection for Unstable Angina Patients and the Level of Inflammatory Factors in Elderly

作　　者：李翔[1] 高毅滨[1] 郑文武[1] 

机构地区：[1]泸州市人民医院心内科,四川泸州646000

出　　处：《四川中医》2016年第9期187-189,共3页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:观察丹红注射液对老年不稳定型心绞痛(UAP)患者的疗效及炎性因子水平的影响。方法:选择医院收治的老年UAP患者86例分为两组,所有患者给予常规治疗,治疗组加用丹红注射液进行治疗。治疗2周后比较两组患者临床疗效及炎性因子水平变化。结果:治疗组心绞痛缓解总有效率为90.70%,明显高于对照组,差异具有显著性(P<0.05);治疗组UAP患者胸闷、胸痛、心悸、胸肋胀满各症状评分均低于对照组(P<0.05);治疗组血清hs-CRP、TNF-α、IL-6浓度较治疗前均显著下降,差异有统计学意义(P<0.05)。两组患者皆未出现不良反应。结论:丹红注射液治疗老年UAP效果显著,安全性高,可在临床上推广。Objective： To study the clinical effects of Danhong Injection on unstable angina. Methods： 86 patients were randomly divided into two groups. All patients were given routine treatment. Except for the routine treatment,the treatment group was given Danhong Injection additionally. Results： In the treatment group,the total efficiency of was 90. 70%,significantly higher than the controlled group which was 79. 07%（ P〈0. 05）; the symptom scores of chest congestion,chest pain and palpitation sternal-rib turgor were significantly lower than those in the controlled group（ P〈0. 05）. The serum hs-CRP,TNF-α,IL-6concentrations in the treatment group were significantly decreased（ P〈0. 05）. There was no adverse reactions in the two groups. Conclusion： Danhong Injection can be used to treat unstable angina with high safety,and is worthy of clinical promotion.

关 键 词：丹红注射液 不稳定型心绞痛 冠心病 炎性因子 

分 类 号：R541.4[医药卫生—心血管疾病]