含谷氨酰胺的肠外营养在严重多发伤患者中的应用研究  

Effect of Parenteral Nutrition With Glutamine in Severe Multiple Trauma Patients

作　　者：梁连生[1] 

机构地区：[1]鄂尔多斯市中心医院ICU,内蒙古东胜017000

出　　处：《内蒙古医学杂志》2016年第6期679-681,共3页Inner Mongolia Medical Journal

摘　　要：目的探讨添加谷氨酰胺的肠外营养对严重多发伤患者的营养状况及预后的影响。方法应用回顾性对照研究方法,将2014年1月至2015年6月我院重症医学科40例接受过肠外营养的严重多发伤患者,根据是否添加有谷氨酰胺的肠外营养,分为治疗组与对照组。治疗组在常规肠外营养的基础上每天给予谷氨酰胺0.4 g/(kg·d),比较两组14 d内营养状况及预后的差异。结果治疗组患者的总蛋白、白蛋白、前白蛋白水平较对照组升高,差异有统计学意义(P<0.05),ICU住院天数、机械通气时间以及病死率方面,治疗组较对照组降低,但差异无统计学意义(P>0.05)。结论添加谷氨酰胺的肠外营养在改善严重多发伤患者的营养状况及预后方面有较好的作用。Objective To explore the effects of parenteral nutrition with glutamine （Gln） to nutritional status and outcomes in severe multiple trauma patients .Methods In this retrospective study ,4 0 patients with severe multiple trauma of our intensive care unit from January ,2 0 1 4 to June ,2 0 1 5 were treated with parenteral nutri-tion ,who were divided into treatment group and control group according to whether or not to add Gln in par -enteral nutrition .The treatment group were given 0 .4 g/kg Gln every day on the basis of conventional therapy , nutritional status and prognosis were compared between two groups within 1 4 days .Results Total protein ,al-bumin ,prealbumin content in treatment group were higher than control group ,the difference was statistically significant（ P 〈 0 .0 5 ） ;hospital stay time ,mechanical ventilation time and mortality rate in treatment group were lower than control group ,but the difference was not statistically significant （P〉 0 .0 5 ） .Conclusion Par-enteral nutrition with Gln is useful in improving the nutritional status and prognosis of patients with severe mul -tiple trauma .

关 键 词：谷氨酰胺 肠外营养 严重多发伤 

分 类 号：R656.7[医药卫生—外科学]