注射用胸腺肽α1稀释液在经口气管插管患者口腔溃疡护理中的应用效果  

Thymosin α1for injection dilution effects on the oral ulcer nursing in the patients with oral endotracheal intubatton

作　　者：金盈盈[1] 姜水娥[1] 许哲[1] 林浙兵 翁杰[1] 王志翊[1] 

机构地区：[1]温州医科大学附属第二医院急诊科,325027

出　　处：《中华现代护理杂志》2016年第12期1755-1757,共3页Chinese Journal of Modern Nursing

基　　金：浙江省自然科学基金资助项目（LY15H150008）;浙江省卫生厅资助项目（2014KYA144）

摘　　要：目的：探讨注射用胸腺肽α1（日达仙）稀释液对经口气管插管患者口腔溃疡的护理疗效。方法选取2014年5月—2015年9月入住温州医科大学附属第二医院ICU的经口气管插管后口腔溃疡患者100例，利用数字表随机法分为观察组和对照组，每组50例。观察组采用注射用胸腺肽α1稀释液进行口腔溃疡护理，对照组采用复方氯己定含漱液进行口腔溃疡护理，观察并比较两组患者口腔溃疡的临床疗效及溃疡愈合时间。结果观察组患者口腔溃疡临床疗效和愈合时间均明显优于对照组，差异有统计学意义（P＜0．05）。结论注射用胸腺肽α1稀释液对经口气管插管致口腔溃疡患者的口腔护理效果优于复方氯己定含漱液，具有临床推广价值。Objective To investigate the nursing effects of Thymosinα1 for injection dilution （Zadaxin dilution） on the patients with oral ulcers caused by oral endotracheal intubation. Methods One hundred patients with oral ulcers caused by oral endotracheal intubation in the ICU of the Second Affiliated Hospital of Wenzhou Medical University from May 2014 to September 2015 were randomly divided into the observation group （n = 50） and the control group （n = 50）according to random number table. For the oral care, the patients with oral ulcers were treated with Thymosin α1 for injection dilution and compound chlorhexidine gargle in the observation group and the control group respectively. Therapeutic effects and ulcer healing time were observed and compared between the two groups. Results The clinical therapeutic effects in the observation group was significantly better than that in the control group （P 〈 0. 05）. The healing time in the observation group was significantly shorter than that in the control group （P 〈 0. 05 ）. Conclusions Thymosinα1 for injection dilution has a better effects than compound chlorhexidine gargle on the treatment of oral ulcers in the patients with oral endotracheal intubation. Thymosin α1 for injection dilution is worthy of clinical promotion.

关 键 词：护理 口腔溃疡 插管术  气管内 注射用胸腺肽α1 稀释液 

分 类 号：R473.78[医药卫生—护理学]