早期肺动脉高压患者右心形态与功能的3.0T磁共振定量评价  

Quantitative evaluation of right heart morphology and function of patients with early pulmonary hypertension via 3.0 T MRI

作　　者：沈训泽[1] 杨立铭[1] 倪瑞军[1] 刘龙斌[2] 韦明珠[1] 张春意[3] 

机构地区：[1]浙江省绍兴市人民医院放射科,浙江绍兴312000 [2]浙江省绍兴市人民医院心内科,浙江绍兴312000 [3]浙江省绍兴市人民医院呼吸内科,浙江绍兴312000

出　　处：《医学影像学杂志》2016年第9期1578-1581,共4页Journal of Medical Imaging

基　　金：浙江省绍兴市科技计划项目(编号:2014B7055)

摘　　要：目的 探讨早期肺动脉高压患者应用3.0T磁共振定量评价患者右心形态与功能的价值。方法 选取2014年12月~2015年12月60例早期肺动脉高压患者作为本次研究观察组,另选择同期健康体检静息状态下肺动脉收缩压（PASP）〈36mm Hg或正常健康者30例为对照组,采用3.0T磁共振检查两组左右心功能、左右室心肌质量及心室质量指数（VMI）。结果 观察组患者右心室EDV、MM及ESV明显高于对照组,而右心室SV及EF明显低于对照组,差异具有统计学意义（P〈0.05）;观察组左心室SV、EDV及EF、PER、PFR明显低于对照组,差异具有统计学意义（P〈0.05）。两组左心室MM及ESV比较,差异无统计学意义（P〉0.05）;而观察组VMI明显高于对照组（P〈0.05）。结论 应用3.0T磁共振定量可有效评价早期肺动脉高压患者心室功能情况,从而为临床诊断、治疗提供参考。Objective To explore the value of 3.0 T MRI in the quantitative evaluation of right heart morphology and function of patients with early pulmonary hypertension. Methods 60 patients with early pulmonary hypertension during a period from De- cember 2014 to December 2015 were selected as a study group and, meanwhile, 30 individuals, whose pulmonary artery systolic pressure （PASP） was 〈 36 mmHg under resting state or who were healthy, were selected as a control group in this work. 3.0 T MRI was employed to test the right and left heart function, left ventricular mass and ventricular mass index （VMI） of the subjects in the two groups. Results The right ventricular EDV, MM and ESV of patients in the study group was significantly higher than those in the control group, while, the right ventricle SV and EF were significantly lower than those in the control group, with sta- tistically significant difference （ P 〈 0.05 ） ; The left ventricular SV, EDV and EF, PER, PFR of patients in the study group were significantly lower than those in the control group and the difference was significant （ P 〈 0.05）. MM and left ventricular ES~ in the two groups were not statistically significant different （ P 〉 0.05）. VMI in the study group was significantly higher than that in the control group （ P 〈 0.05 ）. Conclusion Application of 3.0 T MRI can effectively evaluate the ventricular function of patients with early pulmonary hypertension, thereby providing the reference for the diagnosis and treatment in clinic.

关 键 词：早期肺动脉高压 磁共振成像 右心形态 功能 

分 类 号：R541[医药卫生—心血管疾病] R445.2[医药卫生—内科学]