海南省东方市1938例孕妇TORCH-IgM检测结果分析  

Analysis of TORCH- Ig M test results of 1938 pregnant women in Dongfang City,Hainan Province

作　　者：黎雄 林恒升 岳晓荷 盛国玉 吴珍 

机构地区：[1]东方市东方医院,海南东方572600

出　　处：《中国热带医学》2016年第8期848-850,共3页China Tropical Medicine

摘　　要：目的探讨东方市妊娠妇女弓形体(TOX)、风疹病毒(RUV)、巨细胞病毒(CMV)、单纯疱疹病毒(HSV)的感染状况,分析TORCH感染与不良妊娠之间的关系,为优生优育提供科学依据。方法采用酶联免疫吸附法(ELISA)对来院就诊的1 938例孕妇(包括110例有过不良妊娠者和1 828例正常孕期体检者)进行TORCH-Ig M抗体检测,并对妊娠妇女的户籍、民族和受教育情况进行分析。结果不良妊娠组阳性率TORCH-Ig M感染76例,阳性率为69.09%,其中TOX 16.36%,RUV 14.55%,CMV 58.18%,HSV-I 21.82%,HSV-II 36.36%;正常孕期体检组TORCH-Ig M阳性率为8.48%,其中TOX 1.09%,RUV 0.98%,CMV 4.48%,HSV-I 1.64%,HSV-II 2.52%,各项阳性率前者明显高于后者,差异均有统计学意义(P<0.01)。正常孕期体检组汉族和少数民族分别为6.83%和10.32%,受高等教育和非受高等教育分别为3.65%和10.86%,两组差异均有统计学意义(P<0.05)。结论 CMV和HSV-II是海南东方地区TORCH孕期感染主要病原体。不良妊娠与TORCH病原体感染密切相关,孕妇应对TORCH进行常规筛查,及时发现宫内感染和采取相应有效干预措施。Objective To explore Toxoplasma gondii （TOX）,rubella virus （RUV）,cytomegalovirus （CMV） and herpes simplex virus （HSV） infection status in pregnant women in Dongfang City,as well as the relationship between TORCH infection and adverse pregnancy,so as to provide evidences for eugenics. Methods A total of 1 938 pregnant women （including 110 persons with a history of adverse pregnancy and 1 828 cases of normal pregnancy） were investigated and the TORCH-IgM antibody detections were performed by ELISA. Their registered residence,nationality and education were also investigated and analyzed. Results In the adverse pregnancy group,the positive rates of TOX,RUV,CMV,HSV-I,and HSV-II were 16.36%,14.55%,58.18%,21.82% and 36.36% respectively; in the normal pregnancy group,the positive rates of TOX,RUV,CMV,HSV-I,and HSV-II were 1.09%,0.98%,4.48%,1.64% and 2.52% respectively,and the positive rates of the former group were significantly higher than those of the latter,with statistical significance （P〈0.01）. In the normal pregnancy group,the positive rate of TORCH-IgM was 8.48%,and the rates were 8.39% and 13.34% in the Han nationality group and minority group respectively; the rates were 3.65% and 10.86% in the higher education group and non-higher education group respectively （both P〈0.05）. Conclusion CMV and HSV-II are main pathogens of TORCH infection during pregnancy in east region of Hainan Province. The adverse pregnancy is closely related to the pathogens of TORCH infection. Therefore,pregnant women should take routine screening for TORCH,discover the intrauterine infection,and adopt corresponding effective interventions.

关 键 词：孕妇 TORCH-IGM 不良妊娠 

分 类 号：R531.8[医药卫生—内科学]