Dx-pH检测系统在咽喉反流性疾病中的初步应用  

Preliminary application of Dx-pH monitoring system in laryngopharyngeal reflux disease

作　　者：韩红蕾[1] 赵建辉[1] 张艳丽[2] 王淼[2] 王慧芬[2] 程靖宁[1] 冯云[1] 罗克强[1] 吕秋萍[1] 

机构地区：[1]中日友好医院耳鼻咽喉头颈外科,北京100029 [2]中日友好医院消化科,北京100029

出　　处：《中华耳鼻咽喉头颈外科杂志》2016年第9期666-670,共5页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

摘　　要：目的总结分析Dx－pH检测系统在有咽喉反流性疾病临床症状的患者中的初步使用情况及其临床价值。方法回顾性分析2015年2—12月在中日友好医院耳鼻咽喉头颈外科就诊的54例有咽喉反流性疾病症状的患者资料。所有患者均行咽喉pH检测（Dx－pH）、纤维喉镜检查、反流症状指数（reflux symptoms index，RSI）和反流体征量表（reflux finding score，RFS）评分。 结果54例患者中，Ryan指数阳性者26例，阳性率48.2%。Ryan指数阳性主要表现为直立位Ryan指数阳性（24/26例），占Ryan阳性的92.3%。质子泵抑制剂治疗8周后症状未能完全缓解的22例患者中，13例Ryan指数阳性，阳性率59.1%。Ryan指数阳性与RSI和/或RFS量表评分阳性结果不一致（κ＝－0.013）。 结论尽管与RSI/RFS评分不一致，但是Dx－pH检测系统能检测出咽喉反流事件，帮助临床医师明确诊断咽喉反流性疾病，减少误诊。ObjectiveTo summarize the application and significance of Dx-pH monitoring system in laryngopharyngeal reflux disease. MethodsFifty-four patients who had symptoms of laryngopharyngeal reflux disease in our department from February to December in 2015 were retrospectively analyzed in this study. All patients were evaluated with reflux symptoms index（RSI）, flexible laryngoscope and reflux finding score（RFS）, and larygopharygeal Dx-pH monitoring. ResultsAmong all 54 patients, there were 26 patients whose Ryan score were positive（48.2%）. The positive Ryan score mainly emerged when the patients were upright（24/26, 92.3%）. Among 22 patients whose symptoms could not alleviate well by 8 weeks proton pump inhibitors treatment, there were 13 patients（59.1%） with positive Ryan scores. The Ryan scores were not in good accordance with RSI and RFS（κ=-0.013）. ConclusionsAlthough the results were not in good accordance with RSI/RFS, Dx-pH monitoring system could prove laryngopharyngeal reflux events in patients with laryngopharyngeal reflux disease and help physicians to diagnose.

关 键 词：咽喉反流 PH检测 

分 类 号：R766[医药卫生—耳鼻咽喉科]