大学生寻常性痤疮与幽门螺旋杆菌感染的关系  

Relationships between Helicobacter Pylori Infection and Acne Vulgaris in 980 Cases of College Students

作　　者：王埃胜[1] WANG Ai-sheng(Department of Dermatology, Hospital of Wuhan University, Wuhan University, Wuhan 430072, Chin)

机构地区：[1]武汉大学医院皮肤科,湖北武汉430072

出　　处：《中国皮肤性病学杂志》2016年第10期1024-1025,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的检测在校大学生痤疮患者幽门螺旋杆菌(helicobacter pylori,HP)感染情况,探讨痤疮的发生与幽门螺旋杆菌感染的关系。方法采用C14呼气试验方法对痤疮患者与非痤疮患者进行HP检测和HP阳性率比较,将HP阳性痤疮患者组与HP阳性的非痤疮患者组进行有无胃部症状比较分析,同时将痤疮患者根据症状分级,分析幽门螺旋杆菌感然与痤疮严重程度的关系。结果痤疮患者组HP阳性率(72.00%)明显高于非痤疮患者组HP阳性率(39.23%),HP阳性痤疮患者有胃部症状者(占71.83%)明显多于无胃部症状者(占28.17%),以上差异均有统计学意义。HP阳性非痤疮患者有胃部症状(占47.06%)者低于无胃部症状者(占52.94%),差异无统计学意义。重度痤疮HP阳性率高于轻度痤疮HP阳性率。结论痤疮患者HP检出率高于非痤疮患者;HP阳性病例中有胃部症状痤疮患者病例数高于非痤疮患者;HP阳性与痤疮严重程度相关。提示痤疮的发生与幽门螺旋杆菌感染可能存在关联。因此检测HP以及抗HP感染为痤疮的治疗提供了可能的新方法。Objective To investigate the correlation between Helicobacter pylori （HP） infection and ache vulgaris in college students. Methods HP infection was detected by using C14 exhalation method. The HP positive rates were compared between the ache vulgaris group and the ache vulgaris-free group. The HP positive cases with or without stomach symptom were further analyzed. Additionally, the possible correlation was studied between HP infection and severity of ache vulgaris. Results Seven hundred and ten cases （72. 00% ） were HP positive in ache vulgaris group while 102（39. 23% ） cases were HP positive in ache vulgaris-free group, revealing significant difference. Among the 710 HP positive cases in ache vulgaris group, 510 cases （71.83%） had stomach symptom and 200 cases（28. 17% ） were asymptomatic. On the other hand, among the 102 cases of ache vulgaris-free group, 48 cases （47.05%） were stomach-symptomatic and 54 cases （52. 95% ） were asymptomatic（P 〈0. 01 ）. In the cases of HP positive but no ache, the rate of stomach- symptomatic group is 47.06%, less than the rate of asymptomatic group, no statistical significance. The HP positive rate in severe ache cases was higher than that in mild ache cases. Conclusion The HP positive rate in ache vulgaris patients is obviously greater than that in students without ache vulgaris,wherein the stomachsymptom rate is relatively higher in the HP positive students as well. Furthermore, HP positive rate associates with ache severity. Therefore, the onset of ache vulgaris has relation with HP infection. Detection of HP infection may provide a novel approach for treating ache vulgaris.

关 键 词：寻常性痤疮 幽门螺旋杆菌 

分 类 号：R758.73[医药卫生—皮肤病学与性病学]