我国大气PM_(10)污染对人群死亡率影响的meta分析  

Association between air inhalable particles and mortality in China:a meta-analysis

作　　者：金曼[1] 田璐[1] 佟俊旺[1] 

机构地区：[1]华北理工大学公共卫生学院河北省煤矿卫生与安全实验室,河北唐山063000

出　　处：《环境与健康杂志》2016年第8期725-729,共5页Journal of Environment and Health

基　　金：华北理工大学(原河北联合大学)大学生创新创业训练计划(X2014114)

摘　　要：目的综合相关文献,建立我国PM_（10）与居民死亡率之间的暴露-反应关系。方法通过各数据库和文献检索平台收集2005—2015年发表的符合纳入标准的我国大气PM_（10）污染与居民每日总死亡率、呼吸系统及心脑血管疾病死亡率关系的文献,共纳入20篇共37组相关数据。采用Stata 12.0软件进行meta分析,提取PM_（10）与人群死亡的暴露-反应系数,利用随机或固定效应模型合并效应值,对结果进行敏感性分析、发表偏倚检验及校正。结果建立了我国大气PM_（10）与居民每日死亡之间的暴露-反应关系,我国大气PM_（10）每上升10μg/m3,人群每日总死亡率、呼吸系统疾病和心脑血管疾病死亡率的相对危险度（RR）及95%CI分别为1.001 4（95%CI：1.000 8-1.002 0）,1.001 6（95%CI：0.999 9-1.003 3）,1.002 5（95%CI：1.001 4-1.003 6）。结论大气PM_（10）浓度上升可导致我国居民总死亡率、呼吸系统疾病和心脑血管疾病死亡率增加。Objective To analyze the exposure-response relationship between PM10 and mortality of China. Methods The eligible research papers which studied the association between PM10 and overall mortality of residents, the mortality of respiratory diseases and the mortality of cardiovascular diseases on all kinds of database and the retrieval platform were collected in 2005-2015 and 20 pieces of the papers were adopted in the present study, meta-analysis was conducted by Stata12.0 software,and the exposure-response coefficients of PM10 and mortality were extracted. Results An exposure-response relationship between exposure to ambient PM10 and increased mortality was found. An increase of 10 μg/m3PM10 was associated with estimated relative risk（RR） of daily mortality at 1.001 4（95% CI：1.000 8-1.002 0）,respiratory diseases mortality at1.001 6（95%CI：0.999 9-1.003 3）,cardiovascular diseases mortality at 1.002 5（95%CI：1.001 4-1.003 6）. Conclusion The increase of PM10 concentration may cause the increase of the daily mortality, respiratory diseases mortality and cardiovascular diseases mortality.

关 键 词：PM10 死亡率 暴露-反应关系 META分析 

分 类 号：R122.2[医药卫生—环境卫生学] R181.3[医药卫生—公共卫生与预防医学]