红霉素与阿奇霉素治疗支原体肺炎临床效果比较  

Comparison of clinical effect of erythromycin and azithromycin in the treatment of mycoplasma pneumonia

作　　者：宋海燕 王彬 

机构地区：[1]北京市密云县妇幼保健院儿科,101500

出　　处：《中国基层医药》2016年第19期3022-3025,共4页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的：比较红霉素与阿奇霉素治疗支原体肺炎的临床效果。方法选择小儿支原体肺炎患者120例，按照数字表法将其随机分为研究组和对照组，每组各60例，其中对照组采用红霉素治疗，而研究组则采用阿奇霉素治疗，比较两组患者的临床治疗效果。结果研究组患儿的咳嗽[（3．32±0．52）d]、发热[（3.82±1．53）d]、肺音[（5．64±2．13）d]等临床症状的消失时间较对照组咳嗽[（4．58±0．75）d]、发热[（4．75±1．74）d]、肺音[（7．84±2．85）d]明显缩短，且差异均有统计学意义（t ＝7．54、3．85、5．93，均 P ＜0.05）。研究组患儿的临床治疗总有效率（95．00％）明显高于对照组（83．33％），且差异有统计学意义（χ2＝8．08，P ＜0．05）。研究组与对照组的不良反应发生率比较差异无统计学意义（χ2＝0．64，P ＞0．05）。结论小儿支原体肺炎需早诊断、旱治疗，使用阿奇霉素疗效优于红霉素，可以有效缓解患儿的退热、减轻咳嗽、肺部音等临床症状。Objective To compare the clinical effect of erythromycin and azithromycin in the treatment of mycoplasma pneumonia.Methods 120 children with mycoplasma pneumonia were randomly divided into study group and control group according to digital table method,60 cases in each group.The control group was treated with erythro-mycin,while the study group used azithromycin treatment.Clinical curative effect was compared between the two groups.Results The disappearing time of cough[（4.58 ±0.75 ）d],fever[（4.75 ±1.74）d],pulmonary rales [（7.84 ±2.85）d]of the study group were significantly shorter than those in the control group[（4.58 ±0.75）d, （4.75 ±1.74）d,（7.84 ±2.85）d],and the differences were statistically significant （t =7.54,385,5.93,all P 〈0.05）.The total effective rate in the study group （95.00%）was significantly higher than that in the control group （83.33%）,and the difference was statistically significant （χ2 =8.08,P 〈0.05）.There was no significant difference in the incidence of adverse reactions between the study group and the control group （χ2 =0.64,P 〉0.05 ）. Conclusion Mycoplasma pneumonia in children for early diagnosis and treatment of dry,use of azithromycin curative effect was better than that of erythromycin.It could effectively relieve patients of fever,and alleviate the clinical symptoms of cough,pulmonary rales.

关 键 词：小儿 支原体肺炎 诊断 治疗 

分 类 号：R725.6[医药卫生—儿科]