广东地区10531例不孕症妇女TORCH检测回顾性分析  

Retrospective TORCH Analysis of 10531 Infertile Women in Guangdong

作　　者：杨宁[1] 秦卫兵[1] 钟兴明[1] 苗竹林[1] 崔蓉[1] 王永霞[1] 黄密琼[1] 王小兰[1] 张卓君[1] 

机构地区：[1]广东省计划生育科学技术研究所,广东广州510600

出　　处：《现代医院》2016年第9期1255-1256,共2页Modern Hospitals

基　　金：广东省医学科研基金(编号:A2014201);广东省人口和计划生育委员会科研基金(编号:20110212)

摘　　要：目的了解广东地区不孕症妇女TORCH感染率及不同年龄段不孕症妇女TORCH感染分布情况。方法对2012年1月-2015年6月来我院就诊的10531例不孕症妇女采用酶联免疫法（ELISA）进行TORCHIgM抗体检测。结果广东地区不孕症妇女TORCHIgM抗体阳性率从高至低分别是巨细胞病毒1．7％、单纯疱疹病毒1．1％、风疹病毒1．1％及弓形虫0．7％，TORCH总的感染率为4．6％。在不同年龄段感染特点各有不同，其中单纯疱疹病毒的感染，在20～25岁组阳性率最低为0．7％，26～30岁组阳性率为1．1％，31～35岁组阳性率为1．0％，36～40岁组阳性率为1．8％，大于40岁组阳性率为2．7％，单纯疱疹病毒的感染有随着年龄增大感染率增高的趋势；在不同年龄段弓形虫、风疹病毒和巨细胞病毒的感染无统计学差异。结论不孕症人群中存在一定比例的TORCH感染，要广泛进行卫生宣传教育，减少由TORCH感染引起的不良妊娠的发生。Objective To investigate the TORCH infection rate of infertile women in Guangdong area and the distri- bution of TORCH infection in infertile women of different age groups. Methods From January 2012 to June 2015, 10 531 cases of infertile women were detected by enzyme linked immunosorbent assay （ELISA） for the detection of Toxoplasma, ru- bella virus, cytomegalovirus and herpes simplex virus IgM antibodyin our hospital. Results The positive rate of IgM TORCH antibody in infertile women in Guangdong was 1.7% in Cytomegalovirus, 1.1% in Herpes simplex virus, 1.1% in Rubella virus and 0. 7% in Toxoplasma gondii, and the total positive rate was 4. 6%. The positive rate of herpes simplex virus was 0. 7% in the group aged 20 to 25 years, 1.1% in the group aged 26 to 30 years, 1.0% in the group aged 31to 35 years, 1.8% in the group aged 36 to 40 years and 2. 7% in the group aged more than 40 years, which indicated the infection rate of simple herpes virus went up with the age increasing. The rates of Toxoplasma gondii, rubella virus and cytomegalovirus infec- tion in the groups of different ages were insignificantly different. Conclusion There is a certain proportion of TORCH infec- tion in the infertile population. The health education should be engaged to reduce the incidence of adverse pregnancy induced by TORCH infection.

关 键 词：不孕症 TORCH 阳性率 优生优育 

分 类 号：R711.6[医药卫生—妇产科学]