青年肥胖型高血压的超声诊断研究  

Study on Application of Ultrasound in Diagnosis of Hypertension in Youth Obesity

作　　者：马力丰[1] 罗兵[1] 王义成[1] 刘宏强[1] 袁桂莉[2] 

机构地区：[1]河北北方学院附属第一医院超声医学科,河北张家口075000 [2]河北北方学院附属第一医院心血管内科,河北张家口075000

出　　处：《中国医疗设备》2016年第9期63-66,70,共5页China Medical Devices

摘　　要：目的探讨超声对青年肥胖型高血压患者血管内皮功能、颈动脉内-中膜厚度(Carotid intima-media thickness,CIMT)及心脏功能活动情况的研究。方法应用高分辨率超声检测40例青年肥胖型高血压组、40例青年正常体重高血压组、40例青年肥胖型正常血压组,以及40例对照组血管内皮功能、颈动脉内中膜厚度、颈动脉硬化程度及心脏收缩及舒张功能。结果青年肥胖型高血压组肱动脉基础内径明显高于对照组,差异有统计学意义(P<0.05);青年正常体重高血压组肱动脉基础内径高于对照组,差异有统计学意义(P<0.05);青年肥胖型高血压组血流介导的血管内皮舒张功能(FMD)明显低于对照组(P<0.01)。青年肥胖型高血压组IMT明显高于对照组(P<0.01);青年肥胖型正常血压组IMT与对照组比较无统计学差异(P>0.05)。青年肥胖型高血压组室间隔舒张末期厚度(IVSRTd)、左室后壁舒张末期厚度(LVPWTd)明显高于对照组,差异均具有统计学意义(P<0.05)。青年肥胖型高血压组舒张早期峰值流速Ve显著低于对照组,舒张晚期峰值流速Va明显高于对照组,Ve/Va明显低于对照组和青年肥胖型正常血压组。青年肥胖型高血压组mSLs、mSrLe、mSrLe/mSrLa明显低于对照组,青年肥胖型高血压组mSrLs、mSrLa明显高于对照组,差异均具有统计学意义(P<0.05)。结论高频超声检查能够有效无创地评价患者血管内皮功能、颈动脉内-中膜厚度等,可为患者的临床治疗提供更多、更准确的无创诊断信息。Objective To investigate the application of ultrasound in diagnosis of vascular endothelial functions, carotid intima-media thickness（CIMT） and cardiac functions in youth obesity patients with hypertension. Methods High resolution ultrasound was applied to detect vascular endothelial functions, CIMT, the degree of carotid artery atherosclerosis, cardiac systolic and diastolic functions in Youth Obesity with Hypertension Group（40 cases）, Normal Weight Youth with Hypertension Group（40 cases）, Youth Obesity with Normal Blood Pressure Group（40 cases） and Control Group（40 healthy volunteers）. Results The baseline diameter of brachial artery of Youth Obesity with Hypertension Group was higher than that of Control Group, with statistically significant difference（P〈0.05）; the baseline diameter of brachial artery of Normal Weight Youth with Hypertension Group was higher than that of Control Group, with statistically significant difference（P〈0.05）. The FMD（Flow Mediated Dilation） of vascular endothelium of Youth Obesity with Hypertension Group was significantly lower than that of Control Group（P〈0.01）. IMT of Youth Obesity with Hypertension Group was obviously higher than that of Control Group（P〈0.01）; no statistically significant difference was seen between Youth Obesity with Normal Blood Pressure Group and Control Group（P〉0.05）. IVSTd（Inter-Ventricular Septal Thickness at Diastole） and LVPWTd（Left Ventricular Posterior Wall Thickness at End-Diastole） of Youth Obesity with Hypertension Group were significantly higher than those of Control Group, with statistically significant differences（P〈0.05）. Remarkably lower Ve（Early Diastolic Peak Velocity） and obviously higher Va（End Diastolic Peak Velocity） were seen in Youth Obesity with Hypertension Group in contrast with Control Group; Youth Obesity with Hypertension Group also showed significantly lower Ve/Va than Control Group and Youth Obesity with Normal Blood Pressure Group. The m SLs（Mean Systol

关 键 词：超声诊断 青年肥胖型高血压 颈动脉内中膜厚度 左室舒缩功能 

分 类 号：R197.39[医药卫生—卫生事业管理] TH789[医药卫生—公共卫生与预防医学]