低钾血症与内分泌性疾病的探讨  

Study on the Low Potassium and Endocrine Diseases

作　　者：刘红艳[1] 谷伟军[1] 

机构地区：[1]解放军总医院内分泌科,北京100853

出　　处：《药品评价》2016年第9期21-25,48,共6页Drug Evaluation

摘　　要：低钾血症是临床上最常见的电解质紊乱之一。引起低钾血症的原因有摄入不足、排出过多或者细胞内外钾分布的变化。其中,由内分泌性疾病导致的低钾血症临床上主要有原发性醛固酮增多症、继发性醛固酮增多症、库欣综合征(Cushing综合征)、嗜铬细胞瘤、先天性肾上腺皮质增生症(congenital adrenal hyperplasia,CAH)、Liddle综合征、肾小管酸中毒、低钾周期性麻痹、Bartter综合征、Gitelman综合征等。内分泌性疾病导致低钾血症的原因主要有肾性失钾以及细胞外钾离子转移到细胞内,本文主要介绍这两种原因导致低钾血症的相关内分泌疾病。Low potassium is one of the most common electrolyte disorder in clinic. Causes of low potassium levels are inadequate intake, excessive discharge or changes in the distribution of internal and external potassium. Among them, causes by endocrine disorders of hypokalemia in patients with clinical mainly include primary aldosteronism increase in disorder, and secondary aldosteronism hyperplasia, Cushing＇s syndrome（CS）, pheochromocytoma, congenital adrenal cortical hyperplasia（CAH）, Liddle＇s syndrome, syndrome of renal tubular acidosis and hypokalemia periodic paralysis, Bartter,and Gitelman comprehensive syndrome etc.. The main causes of the disease of the endocrine disease include renal loss of potassium and the transfer of extracellular potassium ions into the cell. This paper mainly introduces the related endocrine diseases of these two factors.

关 键 词：低钾血症 内分泌疾病 肾性失钾 

分 类 号：R58[医药卫生—内分泌] R591.1[医药卫生—内科学]