硝酸铈铵氧化甲苯合成乙酸苄酯的研究  

Study on preparation of benzyl acetate with toluene by ceric ammonium nitrate oxidation

作　　者：柳华锋[1] 徐铭[1] 郭现翠 罗金岳[1] 徐徐[1] 

机构地区：[1]南京林业大学化学工程学院,江苏南京210037

出　　处：《化学研究与应用》2016年第10期1361-1365,共5页Chemical Research and Application

基　　金：国家自然科学基金项目(31470597)资助

摘　　要：以甲苯为原料,硝酸铈铵为氧化剂,通过氧化反应制备了目标产物乙酸苄酯。采用IR、GC-MS和1H NMR等手段对产物进行了表征,确定了产物结构。探讨了催化剂选择、氧化剂选择、乙酰基来源、反应温度、氧化剂用量和反应时间对原料转化率和产物得率的影响;在甲苯5 mmol、冰乙酸为溶剂下,得到适宜的工艺条件为:n(甲苯)∶n(醋酸钠)∶n(硝酸铈铵)=1∶1∶2,氧化铈用量占甲苯质量的3%,反应温度为118℃,反应时间为10 h。在上述优化条件下,产物乙酸苄酯得率为78.9%。Toluene as the raw material,ceric ammonium nitrate as the oxidizing agent,benzyl acetate was prepared by the oxidation reaction of the target product. The structure of the product was identified by IR,GC-MS and 1H NMR. The effects of the kind of cat-alyst ,the kind of oxidant, the kind of acetyl source, the reaction temperature, the amount of oxidant and the reaction time on the re-action rate and the yield of the conversion were discussed. And the optimum conditions were：when toluene was 5 mmol,the solvent was glacial acetic acid,n（toluene） ：n（sodium acetate）：n（CAN） = 1 -1 -2 , the amount of CeO2 was 3%weight of toluene,the reac-tion temperature was 118 ,reaction time was 10 h. In the above conditions,the product yield was 78. 9%.

关 键 词：乙酸苄酯 硝酸铈铵 氧化反应 甲苯 

分 类 号：O625.34[理学—有机化学]