儿童病毒性脑炎继发癫痫的临床特征及脑电图分析  

Clinical features and electroencephalogram analysis of epilepsy secondary to viral encephalitis in children

作　　者：杨中文[1] 高丽[1] 史长松[1] 曹振锋[1] 

机构地区：[1]河南省人民医院儿科,郑州450003

出　　处：《国际医药卫生导报》2016年第20期3088-3091,共4页International Medicine and Health Guidance News

摘　　要：目的探讨儿童病毒性脑炎继发癫痫的临床特征及脑电图情况。方法以确诊病毒性脑炎继发癫痫的46例患儿为观察组，随机抽取同期无继发性癫痫的病毒性脑炎住院患儿69例为对照组；分析观察组继发性癫痫的临床特征及脑电图情况，并比较两组大脑皮质损伤及脑电图检查情况。结果观察组部分性癫痫发作35例，全面性癫痫发作11例，出现癫痫持续状态9例，非癫痫持续状态37例，发作1次者11例，2-6次者29例，〉7次者6例；患儿脑电图显示爆发或长程阵发癫痫波或高幅慢波阵发，异常0、8波持续出现25例、阵发性出现16例、双侧不对称5例；观察组大脑皮质损伤发生率、脑电图重度异常率明显高于对照组，差异有统计学意义（P〈0．01）。结论临床医师应掌握病毒性脑炎继发性癫痫的临床特征及脑电图变化，积极控制惊厥，及时控制癫痫发作，减少癫痫再发，提高临床疗效，改善患儿预后。Objective To explore the clinical features and electroencephalogram conditions of epilepsy secondary to viral encephalitis in children. Methods 46 children confirmed with epilepsy secondary to viral encephalitis were set as an observation group and 69 children with viral encephalitis but without secondary epilepsy a control group. The clinical features and electroencephalogram conditions in the observation group were analyzed. The cerebral cortex injuries and electroencephalogram conditions were compared between these two groups. Results 35 cases occurred partial epileptic seizure and 11 comprehensively epileptic seizure, 9 status epilepticus and 37 non-status epilepticus, and 11 cases suffered 1 time epileptic seizure, 29 cases 2 to 6 times, and 6 cases 〉 7 times in the observation group. The electroencephalogram showed foudroyant epileptic wave, long- range paroxysmal epileptic wave, or high amplitude slow wave paroxysm; abnormal 0 and 5 waves continually appeared in 25 cases, paroxysmally in 16 cases, and dissymmetry in 5 cases. The incidences of cerebral cortex injuries and serious abnormal electroencephalogram were apparently higher in the observation group than in control group, with staitistical differences （P 〈 0.01）. Conclusions The clinicians should know the clinical features and electroencephalogram change of epilepsy secondary to viral encephalitis in children, control the convulsions and epileptic seizure timely, reduce the recurrence chances of epilepsy, enhance the clinical effects, and improve the children＇s prognosis,

关 键 词：病毒性脑炎 儿童 癫痫 临床特征 脑电图 

分 类 号：R720.597[医药卫生—急诊医学]