鼻粘膜扩散系数的测算  

The Measurement of Diffusion Coefficient of Nasal Mucosa

作　　者：刘贵勤[1] 刘娴[1] 张学建 

机构地区：[1]济宁医学院日照校区,济宁276826 [2]泗水县中医院五官科

出　　处：《数理医药学杂志》2016年第10期1487-1488,共2页Journal of Mathematical Medicine

摘　　要：目的:计算鼻粘膜的扩散系数并探讨其应用。方法:利用菲克第一定律,结合鼻粘膜的生理结构特点、用药的剂量及扩散时间,并运用物理计算方法得出了鼻粘膜的扩散系数。结果:人们的鼻粘膜扩散系数与个体差异有关,具有一定的规律性。结论:根据患者鼻粘膜扩散系数,可以优化治疗方案。Objective：To calculate the diffusion coefficient of the nasal mucosa and to discuss its application.Methods：By using the Fick＇s first law of diffusion,combining the physiological structure characteristics of nasal mucosa,the dose,the time of diffusion and by using the physical method obtained the diffusion coefficient of nasal mucosa.Results：People＇s diffusion coefficient of nasal mucosa had relation with the individual difference and got definite regularity.Conclusion：According to the diffusion coefficient of nasal mucosa can optimize the therapeutic schedule about the patient.

关 键 词：分子扩散 菲克第一扩散定律 稳态扩散 鼻腔粘膜 粘膜修复 扩散系数 

分 类 号：R765[医药卫生—耳鼻咽喉科]