2014年湟源县和贵德县健康人群麻疹、风疹抗体水平调查分析  

Analysis on measles and rubella antibody level among Healthy population in Huangyuan County and Guide County in 2014

作　　者：阿克忠[1] 张永基 赵生仓 范丽霞[1] 张万平 祁贵海 

机构地区：[1]青海省疾病预防控制中心,西宁810007 [2]湟源县疾病预防控制中心 [3]贵德县疾病预防控制中心

出　　处：《医学动物防制》2016年第8期832-834,837,共4页Journal of Medical Pest Control

基　　金：国家卫生和计划生育委员会/WHO/UNICEF加强西部地区麻疹监测项目(WPCHN1206297)

摘　　要：目的了解青海省湟源县和贵德县健康人群麻疹、风疹疫苗免疫状况,为制定控制和消除麻疹策略提供参考依据。方法采取随机抽样方法,在每个县随机抽取3个乡镇,每个乡镇抽取1个行政村,调查全年龄组健康人群。应用酶联免疫吸附试验(enzyme-linked immunosorbent assay,ELISA)检测麻疹和风疹Ig G抗体。结果湟源县和贵德县两县共调查364人,其中麻疹Ig G抗体阳性率为87.36%,保护率为61.81%,麻疹抗体几何平均滴度(Geometric Mean Concentration,GMC)为1 997.76 m IU/ml;风疹Ig G抗体阳性率为84.07%,风疹GMC为988.61 m IU/ml;不同年龄组和免疫史不同,抗体水平不同。结论湟源县和贵德县两县麻疹、风疹抗体阳性率不高;含麻疹、风疹成分疫苗接种是切实、有效的。Objective To investigate the measles and rubella antibody level among healthy population in Huangyuan and Guide County of Qinghai Province,so as to provide scientific evidence for formulating measles control and prevention policies.Methods The healthy population aged from 0 to 20 and above 20 years from 3 townships were randomly selected in 2 counties,and the level of measles and rubella Ig G of whose was tested with ELISA method.Results 364 Serum specimens were tested.Measles antibody positive rate was 87.36%,protective rate was 61.81%,and geometric mean concentration（GMC） was 1 997.76 m IU/ml.Rubella antibody positive rate was 84.07%,rubella GMC was 988.61 m IU/ml.The antibody positive rate of whom had immunization history was higher than the non-immunization and the unknown.Conclusion The positive rate of measles and rubella antibody in two counties is not high,and it is feasible and effective to be vaccinated with measles and rubella vaccine.

关 键 词：麻疹 风疹 抗体水平 调查 

分 类 号：R511.1[医药卫生—内科学] R511.2[医药卫生—临床医学]