高血压伴冠状动脉狭窄患者左心房功能实时三平面应变率成像特征及其意义  

Characteristics of left atrial function real-time three plane strain rate imaging in patients with hypertension and coronary artery stenosis and their significances

作　　者：周叶[1] 程云章[1] 黄敬垣[2] 

机构地区：[1]上海理工大学医疗器械与食品学院,上海200093 [2]浙江省浙江医院超声科,浙江杭州310013

出　　处：《吉林大学学报（医学版）》2016年第5期1019-1023,F0003,共6页Journal of Jilin University：Medicine Edition

基　　金：浙江省卫计委中医药科学研究基金项目资助课题(2014ZA001)

摘　　要：目的:探讨原发性高血压患者伴冠状动脉狭窄时左心房功能的实时三平面应变率成像特征,评价其临床应用价值。方法:选取因原发性高血压于浙江医院进行诊治的患者作为研究对象,根据是否并发冠状动脉狭窄分为原发性高血压组(EH组,n=42)和原发性高血压伴冠状动脉狭窄组(EHCHD组,n=40),另外选择健康体检者作为对照组(n=42)。所有研究对象均在接受常规超声心动图检查的基础上,对左心房功能进行实时三平面应变率成像定量分析,并对获得的常规超声心动图参数以及实时三平面应变率参数进行比较分析。结果:与对照组比较,EH组和EHCHD组患者的收缩期左心房平均峰值应变率(SRs)、舒张早期左心房平均峰值应变率(SRe)和SRe/SRa值明显降低(P<0.05),心房收缩期平均峰值应变率(SRa)和舒张晚期应变率达峰时间(Time-SRa)均明显升高(P<0.05);与EH组比较,EHCHD组患者SRs、SRe和SRe/SRa值均明显降低(P<0.05),SRa和Time-SRa明显升高(P<0.05)。结论:实时三平面应变率成像能方便无创准确地定量分析原发性高血压患者伴冠状动脉狭窄时的左心房功能状态,值得在临床上推广应用。Objective：To investigate the characteristics of real-time three plane strain rate imaging of left atrial function in the patients with primary hypertension and coronary artery stenosis, and to evaluate its clinical application value.Methods：Total 82 patients with primary hypertension were selected and divided into primary hypertension group （EH group,n=42）and primary hypertension complicated with coronary artery stenosis group （EHCHD group,n=40）.In addition,the physical examination people were selected as control group （n=42）.All the subjects were examined by conventional echocardiography,and the left atrial function in real-time three plane strain rate imaging was analyzed.The parameters of conventional echocardiography and real-time three plane strain rate imaging were compared.Results：Compared with control group,the systolic left atrial mean peak strain rate （SRs）,early diastolic left atrial mean peak strain rate （SRe）and SRe/SRa of the patients in EH group and＆amp;nbsp;EHCHD group were significantly decreased （P 〈 0.05）;the atrial systolic mean peak strain rate （SRa）and Time-SRa in EH group and EHCHD group were significantly increased （P 〈0.05）.Compared with EH group,SRs,SRe and SRe/SRa in EHCHD group were obviously decreased （P 〈 0.05 ）;SRa and Time-SRa were significantly increased （P 〈0.05）.Conclusion：Real-time three plane strain rate imaging can easily and accurately analyze the left atrial function in the patients with essential hypertension and coronary artery stenosis,it is worth to popularize in clinical application.

关 键 词：超声心动图 三平面应变率 高血压 冠状动脉 狭窄 左心房 

分 类 号：R541.4[医药卫生—心血管疾病]