支气管肺发育不良早产儿呼吸系统疾病预后的研究进展  

Research progress of respiratory system diseases prognosis of premature infant with bronchopulmonary dysplasia

作　　者：韩明珊 谢辰仪 黄花荣[1] 罗焕[1] 谭健辉 吴葆菁[1] 

机构地区：[1]中山大学孙逸仙纪念医院儿科,广州510120

出　　处：《中华妇幼临床医学杂志（电子版）》2016年第5期617-620,共4页Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)

基　　金：广东省自然科学基金项目(2015A030313027)~~

摘　　要：支气管肺发育不良(BPD)是一种最常见的导致慢性肺部病变的疾病。尽管新生儿科诊疗技术不断提升,但BPD发病率仍居高不下。BPD早产儿较非BPD早产儿,具有更高的呼吸系统疾病发生率、呼吸道药物使用率及再次住院率。BPD早产儿肺通气、换气及肺泡弥散功能均较正常足月儿明显受损,这种改变甚至延续到成年人时期,但迄今尚不能确定这种改变与成年人慢性阻塞性肺疾病是否存在相关性。笔者拟就BPD早产儿呼吸系统疾病预后的研究进展进行综述,旨在探索BPD对早产儿呼吸系统疾病预后的远期影响,提高临床对BPD早产儿的重视,为早期预防BPD提供参考依据。Bronchopulmonary dysplasia （BPD） is one the commonest diseases to lead to chronic pulmonary disease. Though many advances in neonatal medical technology, the incidence of BPD remains high. Compared to those without BPD, premature infants with BPD have a higher respiratory morbidity, a greater need for respiratory medications and a higher incidence of rehospitalization. They also have an obviously decreased pulmonary ventilation function, gas exchange function and alveoli diffusion capacity. All these changes can even go down to adulthood which cannot be sure whether it has something to do with chronic obstructive pulmonary disease. In this article, the authors will review on the research progress of pulmonary outcomes of premature infant with bronchopulmonary dysplasia, in order to explore the long term influence of BPD, pay more attention to BPD and its early prevention.

关 键 词：支气管肺发育不良 呼吸系统 肺功能 婴儿 早产 

分 类 号：R722.6[医药卫生—儿科]