献血者HBV标志与受血者HBV感染率的关系  

Relationship Between the HBV Markers in Donors and the Rates of Post-Trans-fusion HBV Infection in Recipients

作　　者：张生昌[1] 王健[1] 翟立炜 宋玉国[1] 张吉林 李若伦[1] 石宏 

机构地区：[1]吉林医学院附属医院,132011

出　　处：《中国输血杂志》1991年第2期63-65,共3页Chinese Journal of Blood Transfusion

摘　　要：用ELISA和斑点分子杂交法在200份HBsAg阴性(RPHA)的合格血液中筛检HBV标志(HBVM):HBVM(-)120份;HBVM(+)80份,其中HBV复制标志(HBVRM)(-)62份,HBVRM(+)18份.接受HBVM(+)血液者其HBV感染率(25.4%)明显高于接受HBVM(-)血液者(3.57%),P<0.01;接受HBVRM(+)血液者的HBV感染率(100%)又明显高于接受HBVRM(-)血液者(2.08%),P<0.001.200 units of eligible blood from donors with negative HBsAg reaction had been tested for hepatitis B virus markers (HBVM), using ELISA and dot-blot hybridization. The results of testing showed that 120 of the 200 units of blood had negative HBVM reaction, and the rest 80 units of blood had positive HBVM reaction. Among these 80 units of blood, 62 units had negative hepatitis B virus replication markers (HBVRM) and the rest 18 units had positive HBVRM. The rate, of post-transfusion HBV infection in the patients received HBVM (+) blood was 25.4%, significantly higher than the rate of post-transfusion HBV infection (3.75%) in the patients received HBVM (-) blood (P<0.01), while the rate of post-transfusion HBV infection in the patients received HBVRM (+) blood was 100%, significantly higher than the rate of post-transfusion HBV infection (2.08%) in the patients received HBVRM (-) blood (P<0.001).

关 键 词：献血员 输血 乙型肝炎 

分 类 号：R512.620.2[医药卫生—内科学]