老老年高血压不同中医证型的临床特征及血小板参数分析  

Clinical characteristics and platelet parameters analysis in senile hypertensive with different syndrome of TCM

作　　者：封锐[1] 魏艺[2] 胡元会[2] 薄荣强 王欢[3] 石晶晶[3] 吴华芹[2] 

机构地区：[1]北京中医药大学,北京100029 [2]中国中医科学院广安门医院心内科,北京100053 [3]中国中医科学院,北京100053

出　　处：《上海中医药杂志》2016年第10期20-23,共4页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局资助项目(JDZX2012109)

摘　　要：目的研究老老年高血压患者不同中医证型的临床及血小板参数特征。方法选取老老年高血压患者127例,其中阴虚阳亢型19例、气虚血瘀型25例、气阴两虚型38例、痰瘀互结型27例、脾肾阳虚型18例;比较各证型患者的临床特征及血小板参数差异。结果 1阴虚阳亢型SBP、DBP、TC、LDL水平以及脑梗死比例(89.5%)明显高于其他证型(P<0.05)。2与其他各证型比较,阴虚阳亢型患者血小板分布宽度(PDW)值最高(P<0.05),平均血小板体积(MPV)值最低(P<0.05);其余证型间PDW、MPV差异无统计学意义(P>0.05);各证型之间比较,血小板计数(PLT)、血小板比容(PCT)、大型血小板比率(P-LCR)差异均无统计学意义(P>0.05)。结论 PDW、MPV与老老年高血压患者阴虚阳亢证关系密切,可以作为辨证的客观参考依据之一。Objective To study the clinical characteristics and platelet parameters of different syndrome of TCM in senile hypertensive. Methods A total of 127 cases of senile hypertensive patients were selected, among which 19 cases with yang excess and yin deficiency ,25 cases with qi deficiency and blood stasis ,38 cases with deficiency of both qi and yin,27 cases with phlegm and blood stasis,18 cases with yang deficiency in spleen and kidney. The clinical features and the platelet parameters in patients with different syndrome types were compared. Results （1）Compared with other types, the levels of SBP, DBP, TC, LDL and ratio of cerebral infarction （89.5%） in patients with yang excess and yin deficiency were obviously increased（ P 〈 0.05 ）. （2） Compared with other types, the platelet distribution width （PDW） in patients with yang excess and yin deficiency was highest（ P 〈 0.05 ）and the mean platelet volume （MPV） was lowest （P 〈 0.05 ） ; there were no significant differences on PDW and MPV among the other syndrome types （ P 〉 0.05 ）. Compared among the different syndrome types, the differences of platelet count （ PLT）, platcletcrit （ PCT）, platelet large cell ratio （P-LCR） were hot statistically significant （ P 〉 0.05 ）. Conclusion PDW and MPV are closely related to the senile hypertensive patients with yang excess and yin deficiency, which could be used as one of the objective reference basis for syndrome differentiation.

关 键 词：老老年高血压 中医证型 血小板参数 

分 类 号：R259[医药卫生—中西医结合]