南宁地区2006～2015年无偿献血者HIV阳性的分布特征  

Distribution features of HIV positive blood donors in Nanning area from 2006 to 2015

作　　者：苏武锦 陈悦 黄茜[2] 

机构地区：[1]南宁中心血站,南宁530003 [2]广西医科大学第三附属医院,南宁530031

出　　处：《重庆医学》2016年第29期4110-4112,4116,共4页Chongqing medicine

摘　　要：[摘要]目的分析南宁地区2006～2015年无偿献血者人类免疫缺陷病毒（HIV）阳性的分布特点，为采供血机构制订有效措施提供数据支持。方法收集南宁地区2006-2015年无偿献血者的相关资料，并对1084889份血液标本进行酶联免疫吸附试验（ELlSA），筛查结果为有反应性的标本，应用蛋白免疫印迹法（Westernblot）进行确认。结果 1084889份献血者标本经确认HIV阳性372例，总阳性率为34．29／10万，呈现增长的趋势（x2趋势=34．717，P〈0．05），互助献血与自愿无偿献血之间的HIV阳性率差异有显著统计学意义（x2=35．625，P〈0．05，OR=1．940，95％CI：1．554～2．421）。男女两性在不同年龄段的差异均有统计学意义（男女分别为x2=37．668，22．984，P〈0．05）。男性阳性率显著高于女性（x2=10．713，P〈0．05，OR=1．436，95％CI：1．155～1．786）。不同文化程度的献血者HIV阳性率差异有统计学意义（x2=39．948，P〈0．05）。不同职业之间献血者HIV阳性率差异有统计学意义（x2=335．260，P〈0．05）。结论南宁牡区2006～2015年无偿献血者HIV感染率呈现逐年增长的趋势，不同献血类型、年龄、性别、职业之间献血者HIV阳性率差异有统计学意义。Objective To analyze distribution features of HIV positive blood donors in Nanning area from 2006 to 2015,in order to provide data support for the blood services to develop effective measures. Methods Collect relevant information on volun- tary blood donor,a total of 1 084 889 blood samples for enzyme linked immunosorbent assay （ELISA）, screening results for reac- tive,using Western blot method for confirmation. Screening results for the reactivity of the samples, then confirmed by Western blot. Results A total of 1 084 889 donors specimens confirmed HIV positive in 372 cases, the total positive rate was 34. 29/ 100 000, showing a growth trend （trend chi-square test Z2 = 34. 717, P 〈0.05）, the difference of positive rate between mutual aid donors and vo!untary non-remunerated blood donors was statistically significant （x2= 35. 625, P〈0.05, OR = 1. 940,95% CI： 1. 554--2. 421）. Differences between men and women at different ages were statistically significant（ men and women respectively x2=37. 668,22. 984,P〈0.05）. Men were significantly higher than that of women（x2=10. 713,P〈0.05,OR= 1. 436,95% CI： 1. 155--1. 786）. There were significant differences in the positive rates of HIV in different cultures（x2 = 39. 948, P〈0.05）. There was significant difference in the positive rate of HIV among blood donors between different occupations （x2= 335. 260, P〈0.05）. Conclusion The HIV infection rate of voluntary blood donors in Nanning area from 2006 to 2015 showed a trend of increasing year by year, there were significant differences in the positive rates of HIV among different blood donors, different ages, different genders and different occupations.

关 键 词：人类免疫缺陷病毒 无偿献血者 输血安全 南宁地区 互助献血者 

分 类 号：R446.6[医药卫生—诊断学] R512.91[医药卫生—临床医学]