实时剪切波弹性成像定量评价正常脾脏组织弹性  

Real-time shear wave elastography in quantitative measurement of tissue elasticity on normal spleens

作　　者：张潇月[1] 唐少珊[1] 

机构地区：[1]中国医科大学盛京附属医院超声科,辽宁沈阳110003

出　　处：《中国医学影像技术》2016年第10期1523-1526,共4页Chinese Journal of Medical Imaging Technology

基　　金：沈阳市科技专项资金(F15-139-9-30)

摘　　要：目的探讨实时剪切波弹性成像(SWE)应用于正常脾脏组织的可行性及影响因素,并建立正常人脾脏组织的杨氏模量值参考范围。方法对280名健康人行肝脏、脾脏弹性模量值检测,记录相关定量分析数据,收集受检者基本信息,分析其性别、年龄、体质量指数(BMI)与肝、脾弹性模量值的相关性。结果 280名健康人正常肝脏杨氏模量均值为(5.54±1.08)kPa,95%CI为(5.41,5.67)kPa;正常脾脏杨氏模量均值为(11.67±2.90)kPa,95%CI(11.33,12.02)kPa。男性与女性间肝、脾弹性测量值差异均有统计学意义(P均<0.05)。年龄、BMI与肝、脾弹性模量值均无明显相关性。男、女性中,肝与脾弹性模量值均无相关性(P均>0.05)。结论 SWE可用以定量评价正常脾脏组织硬度。Objective To explore the feasibility and the impact factors of detecting normal spleen stiffness by real-time shear wave elastography （SWE） and establish a reference range for the Young＇s modulus of spleen in healthy people.Methods SWE detection was performed for 280 healthy volunteers to obtain the Young＇s modulus of liver and spleen, and collect their basic information. The correlation between the sex, age, body mass index （BMI） and the elasticity modulus of liver and spleen were analyzed.Results The Young＇s modulus of the normal liver of 280 healthy people was （5.54±1.08）kPa （95%CI[5.14,5.67]kPa）, while the value of normal spleen was （11.67±2.90）kPa （95%CI[11.33,12.02]kPa）. There were significant differences in the Young＇s modulus of liver and spleen between males and females （both P〈0.05）. Age and BMI were not significantly correlated with the Young＇s modulus of the liver and spleen. In male and female, there were no correlation between normal liver and spleen on the Young＇s modulus （both P〉0.05）.Conclusion SWE is a method to quantitatively evaluate the normal spleen stiffness.

关 键 词：实时剪切波弹性成像 肝脏 脾脏 杨氏模量 

分 类 号：R445.1[医药卫生—影像医学与核医学] R657.6[医药卫生—诊断学]