ICP-MS法测定不同采收期广西产苦丁茶中的8种重金属  

Determination of eight heavy metal elements in the leaves of Ilex kudingcha in different harvests in Guangxi by ICP-MS

作　　者：莫遗盛[1,2] 李岩[2] 冯洁[2] 赖茂祥[3] 黄文琦 

机构地区：[1]广西医科大学第三附属医院,广西南宁530031 [2]广西医科大学药学院,广西南宁530021 [3]广西中医药研究院,广西南宁530022 [4]广西分析测试研究中心,广西南宁530022

出　　处：《华西药学杂志》2016年第5期502-504,共3页West China Journal of Pharmaceutical Sciences

基　　金：国家科技支撑计划课题(2011BAI01B04);广西科学研究与技术开发计划项目(桂科重14124002-3号)

摘　　要：目的采用ICP-MS法测定同一生产基地不同采收期苦丁茶中Cr、Cu、As、Cd、Sn、Sb、Hg、Pb的含量。方法用微波-硝酸消解法处理苦丁茶,在线加入Y元素作为内标来校正样品的基本效应和仪器信号漂移可能对测试过程造成的影响。结果各元素在一定浓度范围内的线性关系良好,r为0.9992~0.9999,RSD为0.02%~2.39%;8种重金属的检出限均≤0.03μg·L^(-1),回收率为96.78%~103.95%。结论苦丁茶中8种重金属元素的含量均符合《药用植物及制剂进出口绿色行业标准》和《中国药典》的标准。OBJECTIVE To determine the contents of Cr, Cu, As, Cd, Sn, Sb, Hg, Pb in the leaves of llex kudingcha C.J. Tseng in different harvests in Guangxi by ICP - MS. METHODS Microwave - nitric acid digested system was used to completely decompose the organic compounds effectually. Internal standard Y element was added on line to correct the basic effect and instrument signal drift, which may cause errors in the process of test. RESULTS All the elements have good hnear relationship in a certain range of concen- tration, and the correlation coefficient ranged from 0. 9992 - 0.9999, and the RSD were between 0.02 to 2.39. The detection limit of these heavy metals was less than 0.03μg·L^-1 , and the recovery was 96.78% - 103.95%. CONCLUSION According to Green Trade Standards of Importing Exporting Medicinal Plants Preparations and Chinese Pharmacopoeia, the contents of eight heavy metals elements in the leaves of I. kudingcha were eligible.

关 键 词：苦丁茶 重金属 电感耦合等离子体质谱 微波-硝酸消解法 质量控制 含量测定 

分 类 号：R917[医药卫生—药物分析学]