连续性血液净化治疗在重症病毒性脑炎伴发癫痫持续状态患者的疗效观察  

Observation of curative effect of continuous blood purification treatment in patients with severe viral encephalitis combined with status epilepticus

作　　者：孙恒斌[1] 余天浩[1] 张宙[1] 

机构地区：[1]南京医科大学附属脑科医院ICU,210029

出　　处：《临床神经病学杂志》2016年第5期363-365,共3页Journal of Clinical Neurology

摘　　要：目的探讨连续性血液净化(CBP)治疗重症病毒性脑炎(SVE)伴发癫痫持续状态(SE)患者的疗效。方法收集24例SVE伴发SE患者,其中15例给予常规治疗为对照组,9例在常规治疗基础上行床旁CBP治疗为治疗组。观察两组的疗效并进行比较分析。结果与对照组比较,治疗组患者发热持续时间、昏迷时间、癫痫持续中止时间、机械通气时间均明显缩短(均P<0.05)。两组间疗效比较差异无统计学意义。结论对于并发SE的SVE患者,常规治疗联合CBP可以较快缓解症状,改善预后。Objective To observe the effect of continuous blood purification（ CBP） in treatment of patients with severe viral encephalitis（ SVE） combined with status epilepticus（ SE）. Methods Twenty-four SVE patients combined with SE were collected. Of which 15 cases received conventional treatment was control group,while 9 cases received CBP on the basis of conventional therapy was treatment group. The two groups were observed for curative effects. Results Compared with the control group,the remission time of fever,consciousness recovery,status epilepticus and mechanical ventilation were significantly shortened in treatment group（ all P〈0. 05）. The curative effects between the two groups were no significantly different. Conclusion For SVE patients with SE,the CBP treatment combined with conventional treatment can quickly relieve symptoms and improve the prognosis.

关 键 词：重症病毒性脑炎 癫痫持续状态 连续性血液净化 预后 

分 类 号：R512.3[医药卫生—内科学]