声学造影在乳腺导管内肿瘤良恶性鉴别中的价值  

Value of Contrast-enhanced Ultrasound in Differentiation of Benign and Malignant Intraductal Tumor of Breast

作　　者：吴欢[1] 肖晓云[1] 管小凤[1] 秦威[1] 陈欣[1] 杨海云[1] 罗葆明[1] 

机构地区：[1]中山大学孙逸仙纪念医院超声科,广州市510120

出　　处：《中国超声医学杂志》2016年第10期880-882,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨声学造影在乳腺导管内肿瘤良恶性鉴别中的价值。方法回顾性分析30例我院收治的乳腺导管内肿瘤(包括导管内乳头状瘤、导管内原位癌及导管内乳头状癌)的常规超声、病理及声学造影的特点,比较良恶性肿瘤之间的差异。重点关注造影前后病灶径线的改变。结果病灶的大小、生长方向、主体回声、边缘、形状、周围导管扩张、病灶内钙化以及彩色多普勒显示的血流情况,在导管内乳头状瘤与导管内癌(包括原位癌和乳头状癌)两组之间,差异无统计学意义。而造影后两组病灶径线均较造影前增大,导管内癌的径线增大明显,两组之间出现显著差异(P<0.05)。结论声学造影有助于鉴别导管内肿瘤的良恶性,导管内恶性肿瘤造影后径线明显增大。Objective To explore the value of contrast-enhanced ultrasound（CEUS） in differentiation of benign and malignant intraductal tumor of breast. Methods 30 cases with intraductal tumor of breast（including intraductal papilloma, intraductal carcinoma in situ and intraductal papillary carcinoma） in our hospital were retrospectively analysed. Characteristics of conventional ultrasound, pathology and CEUS were compared between benign and malignant tumors, focused on the change of diameter of lesions before and after CEUS. Results There were no statistical differences between papilloma and intraductal carcinoma（including carcinoma in situ and papillary carcinoma）, including size, orientation,echo pattern, margin, shape, dilation of duct surrounding the lesion, calcifications and blood flow （showed in color Doppler image） in the masses. Diameter of lesions increased after CEUS in the two groups especially in intraductal carcinoma group. There was statistical difference in two groups（P〈0.05）. Conclusions CEUS can help to differentiate intraductal tumor of breast from benign to malignant, and diameter of malignant lesions increased significantly after CEUS.

关 键 词：声学造影 导管内肿瘤 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]