1例儿童脑动静脉畸形并出血患者的药学监护实践  

Pharmaceutical care on the patient with children's brain arteriovenous malformation and hemorrhage

作　　者：张文[1,2] 高琲[1] 杨孝来[1] 谢华[2] 孙乐维 

机构地区：[1]甘肃省人民医院药剂科,甘肃兰州730030 [2]兰州军区兰州总医院安宁分院药剂科,甘肃兰州730070 [3]天水市第三人民医院药剂科,甘肃天水741000

出　　处：《中国药物应用与监测》2016年第5期277-280,共4页Chinese Journal of Drug Application and Monitoring

摘　　要：1例7岁女性患儿,因发热半天、呕吐1次入院,诊断为脑动静脉畸形并出血、急性扁桃体炎。入院先后给予注射用青霉素钠抗感染、甘露醇注射液脱水降颅内压、碘克沙醇注射液行脑血管造影检查、咪达唑仑注射液镇静、枸橼酸舒芬太尼注射液镇痛、吸入用布地奈德混悬液抗炎等治疗,临床药师对该例患儿进行全程药学监护,为优化治疗方案合理地遴选镇痛镇静药物、抗感染药物和吸入用皮质类固醇激素。同时密切监测患者用药过程中可能出现的电解质、肝功能、肾功能异常等不良反应。治疗10 d后,患儿病情稳定出院。One 7-year-old female patient was admitted to hospital mainly because of fever for half-day and vomitted once. Clinical diagnoses were brain arteriovenous malformation and hemorrhage, acute adenopharyngitis. After hospitalization, the patient received the anti-infective therapy with penicillin sodium, reducing intracranial pressure therapy with mannitol injection, brain angiography with iodixanol injection, sedation therapy with midazolam injection, sufentanil citrate injection was used to analgesia treatment, anti-inflammatory therapy with budesonide suspension for inhalation. Clinical pharmacists supervised the entire treatment in order to optimize the therapeutic regimen by selecting more appropriate analgesic and sedative medications, anti-infective medications and inhaled corticosteroids. Moreover, the adverse drug reactions like electrolyte disturbance, liver function abnormalities and renal insufficiency were monitored regularly. The patient was in a stable condition and discharged on the 10th day.

关 键 词：儿童 脑动静脉畸形 临床药师 药学监护 

分 类 号：R743.4[医药卫生—神经病学与精神病学]