反应性壳聚糖季铵盐改性桑蚕丝纤维的结构与性能  

Structure and properties of B.mori silk fiber treated with reactive quaternary ammonium salt of chitosan

作　　者：张伟[1] 戴新兰[2] 周静洁[2] 朱刚 徐洵 黄颖霞[1] 王笃杰[1] 

机构地区：[1]盐城工学院纺织服装学院,江苏盐城224051 [2]江苏出入境检验检疫局纺织实验室,江苏南京225300 [3]苏州市有冠泰纺织品有限公司,江苏苏州215228

出　　处：《印染助剂》2016年第10期20-23,共4页Textile Auxiliaries

基　　金：江苏省产学研前瞻性联合创新资金研究项目(BY2016065-56);盐城市农业项目(YKN2015006)

摘　　要：基于反应性壳聚糖季铵盐良好的水溶性和反应活性,采用异相法将壳聚糖与2,3-环氧丙基三甲基氯化铵反应,合成2-羟丙基三甲基氯化铵壳聚糖(HTCC),再将HTCC与N-羟甲基丙烯酰胺反应,合成带有反应性基团的水溶性O-甲基丙烯酰胺壳聚糖季铵盐(NMA-HTCC),并将其应用于桑蚕丝纤维的改性,测定改性前后丝纤维微观形态和聚集态结构的变化。结果表明,NMA-HTCC大分子通过与丝纤维之间的交联反应而进入到纤维内部,使改性后丝纤维内部孔隙变小,结构变得更加紧密,结晶度提高,热稳定性增强。利用NMA-HTCC改性真丝纤维作为药物载体,对芦荟提取物蒽醌具有良好的承载及控制释放效果。Based on the good water-solubility and reactivity of reactive quaternary ammonium salt of chi- tosan, with the heterogeneous method, 2-hydroxypropyltrimethyl ammonium chloride chitosan （HTCC） was synthesized using chitosan and 2,3-epoxypropyltrimethyl ammonium chloride, then HTCC was reacted with N-（hydroxymethyl）-acrylamide, and the O-methyl acrylamide quaternary ammonium salt of chitosan （NMA- HTCC） with reactive bonds and water solubility was synthesized. Then NMA-HTCC was applied on the modifi- cation of silk fibers. The micro-morphology and aggregation structure of silk fibers before and after the treat- ment of NMA-HTCC were tested. The results showed that the NMA-HTCC macromolecules went into the in- ternal of fibers by the crosslinking reaction with the silk fibers, which could make the internal pores of silk fi- bers be smaller, the structure be tense, the crystallinity increase and the thermal stability enhance. NMA-HTCC modified silk fiber had good drug loading and release control performance when used as a drug carrier for controlled release of aloe anthraquinone extract.

关 键 词：壳聚糖季铵盐 桑蚕丝 结构 芦荟提取物蒽醌 控制释放 

分 类 号：TQ610.4[化学工程—精细化工]