解剖型纳米羟基磷灰石/聚酰胺66椎间融合器在腰椎XLIF/OLIF手术中的三维有限元分析  

Finite element analysis of the anatomic nano-hydroxyapatite/polyamide 66 cage in XLIF/OLIF surgery

作　　者：彭祥[1] 王文军[1] 晏怡果[1] 左建宏[1] 张健[1] 姚女兆[1] 王程[1] 薛静波[1] 

机构地区：[1]南华大学附属第一医院脊柱外科,湖南衡阳421001

出　　处：《中国临床解剖学杂志》2016年第5期557-562,共6页Chinese Journal of Clinical Anatomy

基　　金：湖南省海外人才与智力引进项目计划(2014)

摘　　要：目的 建立L_（3~5）有效的三维有限元模型,研究解剖型纳米羟基磷灰石/聚酰胺66椎间融合器在XLIF/OLIF手术中的生物力学属性。方法 建立正常人L_（3~5）有限元模型,模拟XLIF/OLIF手术过程分别装配子弹头cage和新型解剖型cage,并对模型进行赋值得到最终有限元模型。对模型施加400 N的轴向压缩及8 Nm力矩的预载荷,使模型产生前屈、后伸、侧弯、旋转运动,分析两种cage的最大应力值和应力分布情况,以及两组L_4-L_5椎体活动度。结果 在6种不同工况下,子弹头cage的最大应力值分别为134.83、79.17、71.31、114.96、76.85、78.77 MPa,解剖型cage最大应力值分别为56.91、61.78、35.82、52.28、31.76、32.45 MPa,解剖型cage比子弹头cage的应力分布要小且分散;两组L_4-L_5椎体活动度均明显小于正常人活动度,且解剖型cage组活动度要小于子弹头cage组。结论 在腰椎XLIF/OLIF微创手术中应用新型解剖型纳米羟基磷灰石/聚酰胺66椎间融合器可以降低最大应力值,避免应力集中,减少椎体活动度,具有较好的生物力学性能。Objective To establish an effective L3~5 three-dimensional finite element model, and study the biomechanical attributes of the anatomical nano-hydroxyapatite/polyamide 66 cage in XLIF/OLIF operation. Methods We established the model of normal lumbar spine（ L3~5） in order to simulate the XLIF/OLIF operation process by assembling a new anatomic cage and a bullet- liked cage, and the assignment model was imported into software to obtain the final finite element model. Pre-load with axial compression of 400 N and 8 Nm torque was imposed on the model, which caused motion of flexion, extension, bending and rotation of the model. the maximum stress, stress distribution of the two kinds of cage and the ROM of the L4~L5 were analyzed. Results Under 6 different operating conditions, the maximum stress of the bullet-liked cage was 134.83, 79.17, 71.31, 114.96, 76.85, 78.77 MPa, and the maximum stress of the anatomic cage was 56.91, 61.78, 35.82, 52.28, 31.76, and 32.45 MPa, respectively. The stress distribution of anatomic cage was smaller and more dispersed than that of the bullet-liked cage. The ROM of L4~L5 in the two groups was significantly less than that of the normal persons,and the ROM of L4~L5 in anatomic cage group was less than that of the bullet- liked cage group. Conclusions The application of the new anatomic nano-hydroxyapatite/ polyamide 66 cage in minimally invasive XLIF/OLIF operation can reduce the maximum stress, circumvent the stress concentration and reduce the activity of vertebral body, proving that it has better mechanical properties.

关 键 词：解剖型椎间融合器 纳米羟基磷灰石/聚酰胺66 XLIF/OLIF 有限元 

分 类 号：R318.01[医药卫生—生物医学工程]