微波辅助合成3,3'-双溴甲基环氧丁烷  

Microwave-assisted Synthesis of 3,3'-Bis-bromo Oxetane

作　　者：刘亚中[1] 岑卓芪 李国平[1] 罗运军[1] LIU Ya-zhong CEN Zhuo-qi LI Guo-ping LUO Yun-jun(School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China)

机构地区：[1]北京理工大学材料学院,北京100081

出　　处：《合成化学》2016年第10期892-894,906,共4页Chinese Journal of Synthetic Chemistry

基　　金：总装预研项目(51328050211)

摘　　要：以三溴新戊醇(TBNPA)为原料,四丁基溴化铵(TBAB)为催化剂,在微波辅助下通过相转移催化合成了3,3'-双溴甲基环氧丁烷(BBMO),其结构经1H NMR和FT-IR确证。最优反应条件为:TBNPA 0.02 mol,n(TBNPA)∶n(TBAB)为100∶3,氢氧化钠溶液浓度为10 mol·L-1,微波(120 W)辐射反应30 min,BBMO收率89%。3,3 ＇-Dis-bromo oxetane was synthesized by microwave-assisted phase transfer catalytic reaction of tribromoneopentyl alcohol （TBNPA） catalyzed by tetrabutylammonium bromide （ TBAB ）. The structure was confirmed by 1H NMR and FT-IR. The optimum reaction conditions were as followed： TBNPA 0.02 mol, c（NaOH） was 10 mol·L^-1, the molar ratio of TBNPA to TBAB was 100：3, reaction under microwave（ 120 W） for 30 rain, the yield was 89%.

关 键 词：三溴新戊醇 四丁基溴化铵 微波辅助 3 3'-双溴甲基环氧丁烷 合成 反应机理 

分 类 号：O624[理学—有机化学]