慢性活动性EB病毒感染  

Chronic active Epstein-Barr virus infection

作　　者：陈丹[1] 钱家鸣[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院消化内科,北京100730

出　　处：《胃肠病学和肝病学杂志》2016年第10期1193-1197,共5页Chinese Journal of Gastroenterology and Hepatology

基　　金：卫生行业科研专项基金(No.201002020)

摘　　要：EB病毒(Epstein-Barr virus,EBV)感染后出现慢性或复发性传染性单核细胞增多症样症状,伴随EBV抗体的异常改变和外周血高EBV-DNA载量,称为慢性活动性EBV感染(chronic active Epstein-Barr virus infection,CAEBV)。其发病机制尚未明确,尚无确切治疗方案,预后差,病死率高。本文就CAEBV发病机制、临床表现、实验室检查及诊治进行综述,以提高临床对CAEBV的诊疗水平。Chronic active Epstein-Barr virus infection（CAEBV）is characterized by chronic or recurrent infectious mononucleosis-like symptoms and high viral load in their peripheral blood. The pathogenesis of CAEBV is unknown and there is no effective treatment. It is rare but severe with poor prognosis and high mortality. In this review, we will sum- marize the pathogenesis, clinical features, therapies and prognosis of CAEBV to improve the management of it.

关 键 词：EB病毒 人类疱疹病毒-4 慢性活动性 

分 类 号：R51[医药卫生—内科学] R725[医药卫生—临床医学]