微生物来源卤化天然产物研究进展  

Research development of halogenated natural products derived microorganisms

作　　者：王荫荫[1] 邵美云[1] 岳昌武[1] 

机构地区：[1]遵义医学院医学与生物学研究中心,贵州省微生物资源及药物开发特色重点实验室,贵州遵义563099

出　　处：《遵义医学院学报》2016年第4期435-440,共6页Journal of Zunyi Medical University

基　　金：国家自然科学基金资助项目(NO:31160004)

摘　　要：卤化天然产物特别是微生物来源卤化天然产物在生理和生物化学上具有重要作用,是抗生素类药物的重要来源,在控制病原微生物特别是耐药菌感染方面发挥着重要作用。本文综述了近年来发现的放线菌、真菌及其它微生物来源的卤化天然产物及其应用前景。Microbial derived halogenated natural products tend possess very important biological and physiological activities,especially against the drug- resistant bacteria infection or antitumor,therefore,is an important source of antibiotic. In this paper,halogenated natural products isolated from actinomycetes,fungi as well as the other microorganisms and their application potential in recent years were reviewed.

关 键 词：卤化天然产物 抗生素 真菌 放线菌 

分 类 号：Q93[生物学—微生物学]