不孕不育妇女支原体感染类型及耐药分析  

Analysis of mycoplasma infection types and drug resistance in infertility women

作　　者：高爽[1] 

机构地区：[1]沈阳市妇婴医院检验科,110011

出　　处：《中国现代药物应用》2016年第19期38-40,共3页Chinese Journal of Modern Drug Application

摘　　要：目的了解本地区不孕不育妇女支原体感染的类型及耐药情况。方法选取618份不孕不育妇女的阴道分泌物标本进行支原体培养及药敏试验。结果 618份送检标本共有376份检出支原体,感染率为60.8%,以单纯解脲支原体(Uu)感染为主,其次是Uu合并人型支原体(Mh)感染,单纯Mh感染最少。体外药敏结果显示:Uu对环丙沙星、氧氟沙星比较耐药;Mh对环丙沙星、氧氟沙星和罗红霉素比较耐药;Uu合并Mh对环丙沙星、司帕沙星、罗红霉素和阿奇霉素耐药率较高。结论本地区不孕不育妇女支原体感染以Uu为主,支原体对强力霉素、交沙霉素和壮观霉素的总体耐药率较低。Objective To understand mycoplasma infection types and drug resistance in infertility women from local area. Methods A total of 618 vaginal secretion samples from infertility women were taken into mycoplasma culture and drug sensitivity test. Results Among 618 tested samples, there were 376 cases with detected mycoplasma, with infection rate as 60.8%. Main infection included single ureaplasma urealyticum（Uu）, followed by Uu complicated with mycoplasma hominis（Mh）, and single Mh accounted for the lowest level. In vitro drug sensitivity test showed Uu resistance to ciprofloxacin and ofloxacin, Mh resistance to ciprofloxacin, ofloxacin and roxithromycin, and Uu combined with Mh resistance to ciprofloxacin, sparfloxacin, roxithromycin and azithromycin. Conclusion Mycoplasma infection in infertility women from local area includes mainly Un, along with overall low drug resistance rate of mycoplasma to doxycycline, josamycin and spectinomycin.

关 键 词：不孕不育 支原体感染 耐药率 

分 类 号：R446.5[医药卫生—诊断学] R711.6[医药卫生—临床医学]