β-羟基-β-甲基丁酸在畜禽营养中作用的研究进展  

Research Progress on β-hyroxy-β-methylbutyrate in Animal Nutrition

作　　者：马友彪 张海军[1] 王晶[1] 武书庚[1] 齐广海[1] 

机构地区：[1]中国农业科学院饲料研究所,农业部饲料生物技术重点开放实验室,北京100081

出　　处：《中国畜牧兽医》2016年第10期2608-2614,共7页China Animal Husbandry & Veterinary Medicine

基　　金：北京市自然科学基金(6132027);家禽产业技术体系北京市创新团队项目(CARS-PSTP);国家科技支撑计划(2011BAD26B04)

摘　　要：β-羟基-β-甲基丁酸(β-hydroxy-β-methylbutyrate,HMB)是亮氨酸代谢的中间产物,对畜禽多种代谢途径发挥着十分重要的调控作用,因此成为了临床医学和畜牧生产两大领域的研究热点。有研究表明,HMB具有促进蛋白质合成、抑制蛋白质降解、提高畜禽生产性能、改善胴体性状、增强免疫机能、减少疾病发生和降低死亡率等作用。作者综述了HMB生成和代谢途径、可能的作用机制及在畜禽生长中的作用,以期为畜禽生产中科学合理应用HMB提供理论依据。β-hyroxy-β-methylbutyrate（HMB）is a metabolite of leucine.HMB has attracted considerable attention of clinical medicine and animal production field,because it is centrally involved in the regulation of multi-biological process and metabolism pathway.HMB has been reported to promote protein synthesis,inhibit protein degradation,improve livestock and poultry production performance and carcass traits,enhance immune function,reduce disease risk and mortality.The synthesis and metabolic pathways,possible mechanism and positive effect of HMB in livestock were reviewed in this paper aiming to supply a useful reference for the application of HMB in animal production.

关 键 词：β-羟基-β-甲基丁酸 蛋白质 骨骼肌 畜禽 

分 类 号：S816.7[农业科学—饲料科学]