多药耐药菌感染患者临床资料分析与预测  

An analysis and predict on clinical surveillance date of multidrug-resistance organism infection

作　　者：张倩茹[1] 李甲[1] 孙向东[1] 姚晓玲[1] 李若洁[1] 徐仲璇[1] 

机构地区：[1]蚌埠市第三人民医院感染管理科,安徽蚌埠233000

出　　处：《中华医院感染学杂志》2016年第20期4648-4650,4674,共4页Chinese Journal of Nosocomiology

基　　金：安徽省高等学校省级自然科学研究基金资助项目(KJ2013Z150)

摘　　要：目的分析医院多药耐药菌的流行特点,为降低和控制多药耐药菌感染提供依据。方法选取2013年1月-2014年12月7 443例住院患者送检标本,采用法国梅里埃公司VITEK-2Compact全自动细菌分析仪进行相关检测分析,数据采用SPSS17.0统计软件进行分析。结果 7 443例住院患者送检标本,1769例检测阳性,阳性率为23.77%;检出多药耐药菌666株,检出率为37.65%;多药耐药菌以产ESBLs大肠埃希菌为主320株占48.05%,其次为多药耐药鲍氏不动杆菌152株占22.08%;在科室分布中,多药耐药菌具有明显科室特点,如ICU的鲍氏不动杆菌占57.89%、外科系统的产ESBLs肠杆菌占45.94%、骨科、烧伤科等具有创面的MRSA占48.84%。结论多药耐药菌感染可根据感染部位、患者基础情况以及入住科室进行预测。OBJECTIVE To analyze the epidemic characteristics of multidrug resistant organisms, so as to provide medical evidence for prevention and control of multidrug-- resistance organism（MDRO） infection. METHODS A to- tal of 7443 samples from hospitalized patients were collected from Jan. 2013 to Apr. 2014. Automatic bacteria an- alyzer （VITEK2 Compact, Merieux Company, France） was used to analyze the samples. And all data were ana- lyzed by using SPSS17.0. RESULTS A total of 1769 strains of samples were positive from the 7443 strains of sam- pies, and the positive rate was 23.77%. A total of 666 strains of MDRO were isolated and the detection rate was 37.65%. The main MDRO was 320 strains of ESBLs producing Escherichia coli, accounting for 48.04%, fol- lowed by 152 strains of MDRO Acinetobacter baumanni, accounting for 22.08%. In different departments, there were obvious characters for MDRO, the A. baumannii accounted for 57. 89% in ICU, and ESBLs producing E. coli accounted for 45.94% in surgery systems, MRSA with wound surface department of orthopaedics, burn de- partment accounted for 48.84%. CONCLUSION The MDRO could be predicted by infection sites, the basic status of patients and departments.

关 键 词：多药耐药菌 临床监测 易感因素 

分 类 号：R181.3[医药卫生—流行病学]